Evidence supporting the use of: Rutin
For the health condition: Edema

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Rutin, a natural flavonoid found in various plants such as buckwheat, citrus fruits, and apples, has been studied for its potential benefits in managing edema, particularly chronic venous insufficiency (CVI) and related vascular conditions. The scientific rationale for its use lies in rutin's ability to strengthen capillaries, reduce capillary permeability, and exert anti-inflammatory and antioxidant effects. Several clinical studies and reviews have investigated flavonoids, including rutin and its closely related compound troxerutin, for their impact on venous tone and microcirculatory function. Some randomized trials and meta-analyses suggest a modest benefit in decreasing leg edema and improving symptoms in patients with CVI, although the quality and size of studies are variable. The European Medicines Agency recognizes "bioflavonoids" (a class including rutin) as traditional herbal medicinal products for relief of symptoms of CVI, but also notes that high-quality clinical evidence is limited. While rutin is not a first-line or universally accepted therapy for edema, particularly where edema is caused by heart, kidney, or liver disease, it has some scientific support for symptom relief in venous-related swelling. The evidence base is not robust enough to warrant a high rating, but its use is more than just tradition, with some mechanistic and clinical data supporting its role.

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Aerva lanata
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Agrimonia pilosa
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Alisma
Allium tuberosum
alpinia galangal
amber
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anthocyanins
apricot
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Arisaema
arjun tree
arjunic acid
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asparagus
atractylodes
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Baccharoides anthelmintica
baicalin
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Baliospermum
bamboo
banana
banyan
Bassia scoparia
bayleaf
bearberry
Bergenia
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betony
big quaking grass
bilberry
bindweed
bioflavonoids
birch
bishop\'s weed
bitter grass
Black Hellebore
blackthorn
Blepharis
blue flag
Boerhavia diffusa
bogbean
Bombax
borage
Borassus aethiopum
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borneol
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bottle gourd
bromelain
buchu
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bupleurum falcatum
burdock
butcher's broom
bасора
cabbage
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cactus
calamus
Calotropis gigantea
Carthamus
Casearia esculenta
celery
Celosia
Centella asiatica
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Chaenomeles lagenaria
chanca piedra
chen pi
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chestnut
Chinese mountain ant
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Chlorophytum
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citrus bioflavonoids
cleavers
Clerodendrum indicum
Clerodendrum phlomidis
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Collinsonia
commiphora
coriander
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cornsilk
couch grass
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deer root
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fang-feng
fernbush
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flat-stem milk-vetch
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forsythia
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fu ling
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jujube
jungli-bean
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knotgrass
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linden
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little ironweed
lodhtree
lophatherum leaf
loquat
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lovage
luffa
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maple
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peach
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