Tayuya (Cayaponia tayuya) is a plant native to South America, especially Brazil, and has a long history of use in traditional medicine by indigenous peoples and in Brazilian folk remedies. Traditionally, Tayuya roots have been used as a diuretic and anti-inflammatory agent, which underpins its use for conditions associated with fluid accumulation, such as edema. The rationale is based on its believed capacity to promote diuresis (increased urine production), thereby reducing fluid retention in tissues.

Scientific studies on Tayuya are limited, but some preclinical research has suggested that extracts of the plant possess anti-inflammatory and antioxidant properties that could indirectly contribute to reducing edema, particularly in the context of inflammation. However, robust clinical trials in humans demonstrating efficacy for edema specifically are lacking. Most of the available evidence remains anecdotal or is based on animal models. Therefore, the primary justification for using Tayuya in the treatment of edema is rooted in traditional usage, with only modest support from early scientific investigation.

In summary, while there is a historical precedent for Tayuya's use in managing edema, high-quality scientific validation is insufficient at this time, and its use for this indication should be considered as complementary and approached with caution.