Evidence supporting the use of: Troxerutin
For the health condition: Edema

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Troxerutin is a flavonoid compound derived from rutin and is commonly used in several countries as a vasoprotective agent. Its use in the treatment and support of edema, especially chronic venous insufficiency-related edema, is supported by scientific studies, though the strength of evidence is moderate. Clinical trials and animal studies suggest troxerutin has anti-inflammatory, antioxidant, and capillary-strengthening properties, which help reduce vascular permeability and improve microcirculation. These effects can decrease fluid leakage from blood vessels into surrounding tissues, thereby alleviating edema.

Several randomized controlled trials and meta-analyses (e.g., in "Phytotherapy Research" and "International Angiology") have reported that troxerutin, alone or in combination with other agents, can reduce leg swelling, improve symptoms of heaviness, and provide relief from edema in patients with chronic venous disorders. However, most studies have relatively small sample sizes and are of moderate methodological quality. There is a need for more large-scale, rigorous clinical trials to confirm these benefits and clarify the optimal dosing and safety profile.

In summary, while troxerutin is not universally accepted as a first-line therapy for edema, its use is supported by a moderate level of scientific evidence, particularly for venous-related edema. Its mechanisms—reducing capillary permeability and inflammation—provide plausible scientific rationale for its effects.

More about Troxerutin
More about Edema

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anthocyanins
apricot
arjun tree
asparagus
waterhyssop
bamboo
bearberry
bilberry
Indian frankincense
bromelain
bupleurum falcatum
burdock
butcher's broom
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cabbage leaf
celery
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Chinese salvia root
citrus bioflavonoids
cucumber
turmeric
dandelion
fish protein
flavonols
forsythia
fu ling
gotu kola
greek mountain tea
onion
hawthorn
hesperidin
horse chestnut
horsetail
Japanese sophora
jujube
lemon
lophatherum leaf
lovage
mannitol
moringa
mustard seed
nettle
papain
parsley
pear
pine bark
pineapple
potassium
protease
pumpkin
quercetin
rutin
scrophularia root
serratiopeptidase
specialized pro-resolving mediators (SPMs)
triphala
trypsin
seaweed
watermelon
sarsaparilla
yellow root
tangerine
xanthium (cockleburs)
atractylodes
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alpinia galangal
punarnava
commiphora
rubia cordifolia
swertia
lingusticum wallichii
goldenrod
prickly ash
lemongrass
silk tree
juniper berries
solomon's seal
siler root
amber
dioscorea
dodder
sweet flag
hyacinth bean
morinda
cornsilk
buchu
birch
couch grass
sheep's sorrel
queen of the meadow
hydrangea
purslane
gentiana macrophylla
cleavers
shepherd's purse
peach
white oak
enzymes blend (proprietary)
Aralia
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Ardisia
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Agrimony
Achyranthes
Abrus
Albizia
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Aerva lanata
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Alisma
Abuta
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Betony
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Blue Flag
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Blackthorn
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Bayleaf
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Bitter Grass
berry
Bogbean
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Banyan
Bioflavonoids
Bombax
Borassus Palm
Borassus aethiopum
Borage
banana
Bupleurum
Baicalin
Bassia scoparia
Black Hellebore
Bergenia
Boerhavia diffusa
Bottle gourd
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Chinese Silkvine
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Coriander
Clerodendrum phlomidis
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Cynomorium
Cinquefoil
Cyathula
Chlorophytum
Curcumen
Centella asiatica
Chanca Piedra
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Calamus
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Cynodon dactylon
Collinsonia
Carthamus
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Echinodorus
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Products containing Troxerutin

We currently have no products on Vitabase that contain this ingredient.