Evidence supporting the use of: Chaste tree
For the health condition: Endometriosis
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Chaste tree (Vitex agnus-castus), also known as chasteberry, has a long history of use in traditional herbal medicine, especially within European and Mediterranean cultures, for managing various gynecological conditions. Its traditional use in supporting endometriosis is based primarily on its reputed effects in balancing female hormones, particularly by influencing prolactin and supporting progesterone production through effects on the pituitary gland. The underlying rationale is that hormonal imbalances are thought to contribute to the development and severity of endometriosis symptoms.
However, direct scientific evidence supporting chaste tree's effectiveness specifically for endometriosis is limited. Most clinical research on chaste tree focuses on its benefits for premenstrual syndrome (PMS), cyclical mastalgia, and menstrual irregularities. A few small studies and anecdotal reports suggest potential symptomatic relief in endometriosis due to its hormonal modulating effects, but robust clinical trials are lacking. The evidence therefore remains mostly traditional, rather than robustly scientific. The rating of 2 reflects the presence of some plausible mechanism and centuries of traditional use, but insufficient direct scientific validation for endometriosis specifically.
Overall, while chaste tree is widely considered safe for most women and is popular in herbal protocols for menstrual and hormone-related issues, its use for endometriosis should be considered adjunctive and not a substitute for evidence-based medical therapies.
Other ingredients used for Endometriosis
black cohoshchaste tree
turmeric
curcumin
DIM (diindolylmethane)
dong quai root
EPA (eicosapentaenoic acid)
evening primrose oil
genistein
ginger
green tea
licorice root
omega-3 fatty acids
resveratrol
specialized pro-resolving mediators (SPMs)
vitamin E
wild yam
zinc
xanthium (cockleburs)
peony
trichosanthes
polyphenols
Achyranthes
Anamu
Anti-aromatase
Boswellic Acid
Boswellia
Cohosh
Caryophyllene
Curcuma
Eupolyphaga sinensis
Other health conditions supported by chaste tree
AmenorrheaBreast Milk (dry up)
Breasts (swelling and tenderness)
Dysmenorrhea
Endometriosis
Fibroids (uterine)
Infertility
Menopause
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Miscarriage (prevention)
Mood Swings
Night Sweating
Ovarian Pain
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
PMS Type S
Progesterone (low)
Puberty (hormone balancer)
Sex Drive (low)
Products containing chaste tree
Vitabase
Active Woman's Multi
Pure Encapsulations
Chaste Tree
Pure Encapsulations
Chaste Tree
Metagenics
Chasteberry Plus
Metagenics
Fem EstroPlex®
Designs For Health
FemGuard+Balance™
Thorne
Meta-Balance
Douglas Laboratories
TestoQuench ™ for Women
Integrative Therapeutics
Vitex Extract
Vitabase
Women's Support