Evidence supporting the use of: Chinese peony
For the health condition: Endometriosis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Paeonia lactiflora, commonly known as Chinese peony, has a long history of use in Traditional Chinese Medicine (TCM) for the management of gynecological disorders, including endometriosis. In TCM, Chinese peony root (Bai Shao) is believed to nourish the blood, regulate menstruation, and alleviate pain, which are considered beneficial actions for women suffering from symptoms of endometriosis such as dysmenorrhea and pelvic pain. Paeonia is frequently included in classic herbal formulas like "Dang Gui Shao Yao San" or "Gui Zhi Fu Ling Wan," which are prescribed for menstrual irregularities and pelvic masses.

While traditional use is well established, scientific validation is limited. Some in vitro and animal studies have suggested that active constituents in Chinese peony, such as paeoniflorin, may have anti-inflammatory, immunomodulatory, and antispasmodic effects. These effects could theoretically address the inflammation and abnormal tissue growth associated with endometriosis. However, robust clinical trials in humans specifically evaluating the efficacy of Chinese peony for endometriosis are lacking. Most published evidence consists of small-scale studies, animal experiments, or investigations of multi-herb formulations, making it difficult to isolate the effect of Chinese peony alone.

In summary, the use of Chinese peony for endometriosis is primarily justified by traditional medical practice, with some preliminary preclinical data but insufficient high-quality clinical evidence.

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