Evidence supporting the use of: Commiphora wightii
For the health condition: Endometriosis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Commiphora wightii (also known as guggul) is an important herb in Ayurvedic medicine, traditionally used for its anti-inflammatory, lipid-lowering, and general health-promoting properties. Its use in endometriosis is not well-documented in either traditional Ayurvedic texts or modern scientific literature. However, guggul is sometimes recommended in traditional medicine for a range of gynecological disorders, particularly those characterized by inflammation or pain, due to its reputed anti-inflammatory and analgesic actions. There are a few anecdotal or generalized mentions of its use for menstrual disorders, which may overlap with endometriosis symptoms, but there is no direct, robust evidence—clinical or preclinical—specifically supporting its effectiveness for endometriosis. Scientific studies have investigated the anti-inflammatory effects of guggulsterones (the bioactive compounds in Commiphora wightii), but these have not been systematically extended to endometriosis models. Overall, while there is a traditional rationale for the use of Commiphora wightii in some gynecological contexts, evidence for its specific benefit in endometriosis is weak and largely indirect.

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