Evidence supporting the use of: Vitex Agnus-Castus
For the health condition: Endometriosis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitex Agnus-Castus (also known as chaste tree) is traditionally used in herbal medicine for various gynecological conditions, particularly those involving menstrual irregularity and premenstrual symptoms. Its primary historical use is to support hormonal balance, especially in cases of luteal phase defects and symptoms associated with premenstrual syndrome (PMS). The rationale for its use in endometriosis is largely extrapolated from its broader applications in women’s reproductive health, rather than from any direct evidence or long-standing tradition specifically targeting endometriosis.

While there is some scientific evidence that Vitex Agnus-Castus can influence pituitary hormones, particularly prolactin, and may help with menstrual regulation, there is very limited direct scientific research or clinical trial data supporting its efficacy for endometriosis specifically. Most of the available clinical research focuses on PMS, mastalgia, and cycle irregularities. Endometriosis is a complex, estrogen-dependent disease involving inflammation and ectopic endometrial tissue, and there is little evidence suggesting that Vitex can directly affect these mechanisms in humans. Thus, its use for endometriosis is primarily traditional and not strongly evidence-based.

In summary, while Vitex Agnus-Castus is commonly used in traditional herbal medicine to address female reproductive issues, its use for endometriosis is based on historical practice and theoretical benefit rather than on robust scientific validation.

More about Vitex Agnus-Castus
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