Evidence supporting the use of: L-glutamine
For the health condition: Endurance (lack of)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
L-glutamine is an amino acid that has been studied for its potential role in supporting endurance and recovery in athletes and individuals experiencing physical fatigue. The rationale for its use is based on the observation that glutamine levels can decrease after prolonged, intense exercise, which may impact immune function and muscle recovery. Some researchers have hypothesized that glutamine supplementation could help restore these levels, reduce muscle soreness, and support endurance capacity.
However, the scientific evidence supporting the use of L-glutamine specifically for improving endurance is limited and inconsistent. Several studies have found that glutamine supplementation does not significantly enhance endurance performance, reduce perceived fatigue, or improve time to exhaustion in healthy athletes. Systematic reviews and meta-analyses generally conclude that while glutamine may help maintain immune function after strenuous exercise, it does not provide a clear benefit in terms of increasing endurance or exercise performance metrics.
In summary, while there is a theoretical basis and some preliminary research suggesting glutamine could play a role in recovery, the overall scientific evidence supporting its use for improving endurance performance is weak. Its primary benefit may relate more to immune support than to direct enhancement of endurance. As such, glutamine supplementation is not widely recommended as a performance enhancer for endurance athletes based on current evidence.
Other ingredients used for Endurance (lack of)
acetyl l-carnitineashwagandha
beta-alanine
coenzyme Q10 (CoQ10)
cordyceps
creatine monohydrate
eleuthero
ginseng
l-alanyl-l-glutamine
l-citrulline
l-glutamine
magnesium
milk
phenolic acids
rhodiola
sphaeranthus indicus
spirulina
vitamin B12
jiaogulan
siler root
electrolytes blend (proprietary)
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Alpha polylactate
Antler
Arginine malate
Alpha glyceryl
Bacteria
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
esters
Other health conditions supported by l-glutamine
Abdominal PainAthletic and Exercise Aids
Autoimmune Disorders
Body Building
Burns and Scalds
Cancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Colitis
Convalescence
Cuts
Debility
Diarrhea
Digestion (poor)
Endurance (lack of)
Energy (lack of)
Enteritis
Exercise
Gastritis
Inflammation
Inflammatory Bowel Disorders
Injuries
Irritable Bowel Syndrome
Leaky Gut Syndrome
Products containing l-glutamine
Douglas Laboratories
5-HTP Plus Formula
Designs For Health
Amino-D-Tox™
Designs For Health
Amino-D-Tox™
Pure Encapsulations
Amino-NR
Pure Encapsulations
Amino Replete
Designs For Health
BCAA Powder with L-Glutamine
Metagenics
Clear Change 10-Day Detox Program with UltraClear Plus Berry
Metagenics
Clear Change 10-Day Detox Program with UltraClear Plus pH
Metagenics
Clear Change 10-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics
Clear Change 10-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics
Clear Change 10-Day Detox Program with UltraClear Plus Vanilla
Metagenics
Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics
Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
Metagenics
Clear Change 28-Day Detox Program with UltraClear Plus Berry
Metagenics
Clear Change 28-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics
Clear Change 28-Day Detox Program with UltraClear Plus pH Vanilla
Metagenics
Clear Change 28-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics
Clear Change 28-Day Detox Program with UltraClear Plus Vanilla
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Integrative Therapeutics
Detoxication Factors
Integrative Therapeutics
Detoxication Factors
Thorne
EnteroMend NSF
Pure Encapsulations
EpiIntegrity
Pure Encapsulations
G.I. Fortify
Pure Encapsulations
G.I. Fortify
Pure Encapsulations
G.I. Integrity
Pure Encapsulations
G.I. Integrity
Designs For Health
GI Revive®
Designs For Health
GI Revive®
Metagenics
GI Sustain™ Powder
Metagenics
Glutagenics® powder
Integrative Therapeutics
Glutamine Forte Drink Mix
Vitabase
HGH Complex
Designs For Health
IBSynergy™
Klean Athlete
Klean Essential Aminos + HMB®
Klean Athlete
Klean Isolate ™
Thorne
L-Glutamine
Pure Encapsulations
l-Glutamine
Designs For Health
L-Glutamine
Douglas Laboratories
L-Glutamine
Pure Encapsulations
l-Glutamine 500 mg
Pure Encapsulations
l-Glutamine 850 mg
Pure Encapsulations
l-Glutamine 850 mg
Designs For Health
L-Glutamine Powder
Designs For Health
L-Glutamine Powder
Douglas Laboratories
L-Glutamine Powder
Thorne
L-Glutamine Powder NSF
Pure Encapsulations
Liver G.I. Detox
Thorne
MediClear Plus
Integrative Therapeutics
Multiplex-1 No-Iron
Douglas Laboratories
Muscle Protect™ with HMB®
Designs For Health
Neurolink™
Integrative Therapeutics
Nutrivitamin No-Iron
Pure Encapsulations
PureBi•Ome™ G.I.
Metagenics
Ultra Potent-C 1000
Metagenics
Ultra Potent-C Chewable
Metagenics
UltraClear Plus® Detox Powder
Metagenics
UltraClear Plus Detox Powder Berry
Metagenics
UltraClear Plus Detox Powder Pineapple/Banana
Metagenics
UltraClear Plus pH Detox Powder Pineapple/Banana
Metagenics
UltraClear Plus pH Detox Powder Vanilla
Metagenics
UltraClear RENEW Detox Powder Berry
Metagenics
UltraClear RENEW Detox Powder Chai
Metagenics
UltraClear RENEW Detox Powder Vanilla
Pure Encapsulations
UltraDetox 10-Day Pure Pack
Metagenics
UltraGI Replenish® Chocolate
Metagenics
UltraGI Replenish Chocolate
Metagenics
UltraGI Replenish Vanilla
Metagenics
UltraGI Replenish Vanilla
Metagenics
UltraInflamX Plus 360°® Chocolate/Orange
Metagenics
UltraInflamX Plus 360° Mango
Metagenics
UltraInflamX Plus 360° Mango
Metagenics
UltraInflamX Plus 360° Orange
Metagenics
UltraInflamX Plus 360° Original Spice
Metagenics
UltraInflamX Plus 360° Pineapple/Banana
Metagenics
UltraInflamX Plus 360° Pineapple/Banana