Evidence supporting the use of: 1,3,7-Trimethylpurine-2,6-dione
For the health condition: Energy (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

1,3,7-Trimethylpurine-2,6-dione is the chemical name for caffeine, a well-known stimulant found in coffee, tea, and various energy products. Its use for combating lack of energy is strongly supported by scientific evidence. Caffeine acts as a central nervous system stimulant by antagonizing adenosine receptors, which increases alertness and reduces perceived fatigue. Numerous clinical studies have demonstrated that caffeine consumption can improve subjective feelings of energy, increase wakefulness, boost cognitive performance, and enhance physical endurance. Meta-analyses and systematic reviews confirm that caffeine is effective in reducing fatigue and improving both mental and physical performance in a dose-dependent manner, with effects observable in both habitual and non-habitual users. Caffeine has a long history of traditional use for increasing alertness and energy, but its efficacy is also robustly validated in scientific literature, particularly for short-term, acute improvements in energy and alertness. However, chronic use can lead to tolerance, and excessive intake may cause side effects such as jitteriness, insomnia, or increased heart rate. Overall, caffeine (1,3,7-Trimethylpurine-2,6-dione) is one of the most thoroughly studied and validated substances for supporting energy and reducing fatigue.

More about 1,3,7-Trimethylpurine-2,6-dione
More about Energy (lack of)

Other ingredients used for Energy (lack of)

7-Keto-DHEA
acai berry
acetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha d-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
aspartic acid
beta-alanine
biotin
black pepper
bасора
caffeine
capsaicinoids
coconut milk
coenzyme Q10 (CoQ10)
coffee fruit
cordyceps
creatine monohydrate
eleuthero
folate
fructose
ginseng
greens blend (proprietary)
guarana
guayusa
l-alanyl-l-glutamine
l-carnitine
l-glutamine
l-glycine
l-leucine
l-tyrosine
maca
magnesium
malic acid
maltodextrin
medium chain triglycerides (MCT)
microbial enzymes (proprietary)
milk
Acetyl-L-Tyrosine
nettle
pantothenic acid (vitamin B5)
pollen
protein
pyrroloquinoline disodium salt
rhodiola
rosemary
sage
shiitake mushroom
black ginger
sphaeranthus indicus
spirulina
succinic acid
tongkat ali
almond fruit
vegetable blend (proprietary)
velvet bean
vitamin B
vitamin B12
vitamin B6
whey protein
zinc
suma
jiaogulan
alpinia galangal
commiphora
bee pollen
lemongrass
siler root
cistanche
sweet flag
electrolytes blend (proprietary)
trace minerals
yerba mate
wheat germ
algae
1,3,7-Trimethylpurine-2,6-dione
Aralia
akebia
Alpha polylactate
Antler
Agastache
Arginine Creatine
Ardisia
Arginine malate
Anamu
Areca
adenosine triphosphate (ATP)
Algal protein
Amor seco
Arginine silicate
Atractylone
Animal protein
Beta Phenethylalamine
Blackthorn
Beta-hydroxybutyrate
Beef liver
Bovine Protein
berry
Ba Ji Tian
Borassus Palm
Borassus aethiopum
banana
Baobab
Borneol
Chia seed
Coconut
Cinnamomum
Coenzyme A
coconut oil
Codonopsis
Cynomorium
Catecholamine
Chlorophytum
Chuchuhuasi
Curcumen
Coca
Chicken
cola nut
Dendrobium
Deer Root
Deer Velvet
Dragonhead
Dextrates
D-Ribose
Dextrose
Erodium cicutarium
Egg
Elk antler
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Ephedrine
Egg protein
glucose
Ketone Salts
Milk Protein
peanut
Wheat

Products containing 1,3,7-Trimethylpurine-2,6-dione

We currently have no products on Vitabase that contain this ingredient.