Evidence supporting the use of: Arginine silicate
For the health condition: Energy (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Arginine silicate is a compound that combines L-arginine, an amino acid, with silicon. Its use in supporting or treating lack of energy is based on several small-scale clinical studies, though the overall evidence remains limited. Arginine is a precursor for nitric oxide (NO), a molecule that plays a critical role in vasodilation (widening of blood vessels), thereby potentially improving blood flow and oxygen delivery to tissues. Improved circulation may contribute to enhanced physical performance and reduced feelings of fatigue.

A few studies, such as those published in the Journal of the International Society of Sports Nutrition (2015, 2016), have shown that arginine silicate supplementation can improve perceived energy, mental focus, and exercise performance in athletes and healthy adults. These studies are promising but involve relatively small sample sizes and short durations. The mechanism is thought to be linked to increased nitric oxide production and improved silicon bioavailability, supporting vascular health and possibly cognitive function.

However, there is a lack of large, long-term randomized controlled trials directly evaluating arginine silicate for general fatigue or chronic lack of energy in non-athletic populations. Most evidence pertains to short-term improvements in exercise performance or mental focus. As such, while there is some scientific rationale and preliminary evidence, the overall strength of data is moderate to low (2/5). Further research is needed to conclusively establish its efficacy for treating or supporting energy in the general population.

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7-Keto-DHEA
Acai berry
Acetyl L-carnitine
adenosine 5-triphosphate disodium (ATP)
Alpha D-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
aspartic acid
beta-alanine
biotin
black pepper
bасора
caffeine
capsaicinoids
coconut milk
coenzyme Q10 (CoQ10)
coffee fruit
cordyceps
creatine monohydrate
eleuthero
folate
fructose
ginseng
greens blend (proprietary)
guarana
guayusa
L-alanyl-L-glutamine
l-carnitine
L-glutamine
L-glycine
L-leucine
l-tyrosine
maca
magnesium
malic acid
maltodextrin
medium chain triglycerides (MCT)
Microbial enzymes (proprietary)
Milk
Acetyl-L-Tyrosine
Nettle
pantothenic acid (vitamin B5)
pollen
protein
pyrroloquinoline disodium salt
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rosemary
sage
shiitake mushroom
black ginger
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spirulina
succinic acid
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vegetable blend (proprietary)
velvet bean
vitamin B
vitamin B12
vitamin B6
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suma
jiaogulan
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commiphora
bee pollen
lemongrass
siler root
cistanche
sweet flag
electrolytes blend (proprietary)
trace minerals
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wheat germ
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1,3,7-Trimethylpurine-2,6-dione
Aralia
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antler
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arginine creatine
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Arginine malate
anamu
Areca
Adenosine triphosphate (ATP)
Algal protein
Amor seco
Arginine silicate
atractylone
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beta phenethylalamine
blackthorn
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Products containing Arginine silicate

We currently have no products on Vitabase that contain this ingredient.