Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Coenzyme Q10 (CoQ10) is a naturally occurring antioxidant present in most cells, where it plays a key role in mitochondrial energy production. CoQ10 participates in the electron transport chain, facilitating ATP (adenosine triphosphate) synthesis, the primary energy currency of the cell. Because of this central function, CoQ10 has been studied for its potential to improve symptoms of energy deficiency, such as fatigue.

Clinical research provides some support for CoQ10 supplementation in populations with specific energy-related disorders. For example, studies have shown benefit in patients with chronic fatigue syndrome, fibromyalgia, and certain mitochondrial disorders, where CoQ10 levels may be deficient or mitochondrial function is impaired. Additionally, CoQ10 supplementation is well established in improving symptoms and quality of life in patients with heart failure, where fatigue is a common symptom. However, evidence for its effectiveness in otherwise healthy individuals experiencing general fatigue or low energy is limited and inconsistent. Most studies in healthy adults report minimal or no significant improvement in subjective energy levels.

In summary, while the biological mechanism for CoQ10’s role in cellular energy production is clear and there is modest evidence for benefit in clinical populations with energy metabolism disorders, robust data supporting its use for everyday fatigue or low energy in healthy people are lacking. Thus, the overall strength of evidence for CoQ10 as a general energy booster is moderate to low.

More about coenzyme Q10 (CoQ10)
More about Energy (lack of)

Other ingredients used for Energy (lack of)

Other health conditions supported by coenzyme Q10 (CoQ10)

Products containing coenzyme Q10 (CoQ10)

Pure Encapsulations Athletic Nutrients
Douglas Laboratories Citrus-Q10 ™
Douglas Laboratories Co-Enzyme Q10 Softgel
Douglas Laboratories Coenzyme Q-10 with Lipoic Acid
Douglas Laboratories Coenzyme Q-10 with Lipoic Acid
Integrative Therapeutics CoQ10
Integrative Therapeutics COQ10 100 mg Tropical
Pure Encapsulations CoQ10 120 mg
Pure Encapsulations CoQ10 120 mg
Pure Encapsulations CoQ10 120 mg
Integrative Therapeutics COQ10 200 mg Chocolate 30 chew tabs
Pure Encapsulations CoQ10 250 mg
Pure Encapsulations CoQ10 30 mg
Pure Encapsulations CoQ10 500 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 60 mg
Pure Encapsulations CoQ10 l-Carnitine Fumarate
Thorne CoQ10 Q-Best 100
Metagenics CoQ10 ST®-100 mg
Metagenics CoQ10 ST-100 mg
Metagenics CoQ10 ST-200 mg
Integrative Therapeutics Detoxication Factors
Integrative Therapeutics Detoxication Factors
Pure Encapsulations Energize Plus™ Pure Pack
Pure Encapsulations Hair/Skin/Nails Ultra
Thorne Heart Health Complex Q-10 Plus
Integrative Therapeutics K-PAX MitoNutrients
Vitabase Life's Essentials Plus
Designs For Health Mito-NR™
Pure Encapsulations Mitochondria-ATP
Designs For Health Mitochondrial NRG™
Pure Encapsulations NeuroMood Pure Pack
Metagenics NutraGems® CoQ10 300
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Pure Encapsulations O.N.E.™ Multivitamin
Thorne Omega-3 w/ CoQ10
Thorne Ovarian Care
Integrative Therapeutics ProThrivers Wellness Flav Complex
Pure Encapsulations PureGenomics® UltraMultivitamin
Designs For Health Q-Evail® 100
Designs For Health Q-Evail® 200
Pure Encapsulations Q-Gel® (Hydrosoluble™ CoQ10) 100 mg
Thorne Red Yeast Rice + CoQ10 Choleast
Pure Encapsulations Renual
Pure Encapsulations RevitalAge™ Nerve
Pure Encapsulations RevitalAge™ Ultra
Designs For Health RYR Synergy™
Pure Encapsulations SR-CoQ10 with PQQ
Vitabase Super Fat Burner
Pure Encapsulations Ubiquinol-QH 100 mg
Pure Encapsulations Ubiquinol-QH 200 mg
Pure Encapsulations Ubiquinol VESIsorb®
Integrative Therapeutics UBQH 100 mg
Douglas Laboratories Ultra Preventive 50+ -EZ Swallow
Douglas Laboratories Ultra Preventive One Daily
Pure Encapsulations Ultra Pure Pack
Pure Encapsulations UltraDetox 10-Day Pure Pack
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Metagenics Wellness Essentials Brain Health Daily Packs