Relationship: Energy (lack of) and coenzyme Q10 (CoQ10)

Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Energy (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Coenzyme Q10 (CoQ10) is a naturally occurring antioxidant present in most cells, where it plays a key role in mitochondrial energy production. CoQ10 participates in the electron transport chain, facilitating ATP (adenosine triphosphate) synthesis, the primary energy currency of the cell. Because of this central function, CoQ10 has been studied for its potential to improve symptoms of energy deficiency, such as fatigue.

Clinical research provides some support for CoQ10 supplementation in populations with specific energy-related disorders. For example, studies have shown benefit in patients with chronic fatigue syndrome, fibromyalgia, and certain mitochondrial disorders, where CoQ10 levels may be deficient or mitochondrial function is impaired. Additionally, CoQ10 supplementation is well established in improving symptoms and quality of life in patients with heart failure, where fatigue is a common symptom. However, evidence for its effectiveness in otherwise healthy individuals experiencing general fatigue or low energy is limited and inconsistent. Most studies in healthy adults report minimal or no significant improvement in subjective energy levels.

In summary, while the biological mechanism for CoQ10’s role in cellular energy production is clear and there is modest evidence for benefit in clinical populations with energy metabolism disorders, robust data supporting its use for everyday fatigue or low energy in healthy people are lacking. Thus, the overall strength of evidence for CoQ10 as a general energy booster is moderate to low.

More about coenzyme Q10 (CoQ10)
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Other ingredients used for Energy (lack of)

1,3,7-Trimethylpurine-2,6-dione
7-Keto-DHEA
Acai berry
Acetyl L-carnitine
Acetyl-L-Tyrosine
adenosine 5-triphosphate disodium (ATP)
Adenosine triphosphate (ATP)
Agastache
Akebia
Algae
Algal protein
Almond fruit
Alpha D-ribofuranose
Alpha polylactate
alpha-ketoglutarate (AKG)
alpinia galangal
amino acids
Amor seco
anamu
animal protein
antler
Aralia
Ardisia
Areca
arginine creatine
Arginine malate
Arginine silicate
ashwagandha
aspartic acid
atractylone
ba ji tian
banana
baobab
bee pollen
Beef liver
berry
beta phenethylalamine
beta-alanine
beta-hydroxybutyrate
biotin
black ginger
black pepper
blackthorn
Borassus aethiopum
borassus palm
borneol
bovine protein
bасора
caffeine
capsaicinoids
catecholamine
chia seed
Chlorophytum
chuchuhuasi
Cinnamomum
cistanche
coca
coconut
coconut milk
coconut oil
Codonopsis
Coenzyme A
coenzyme Q10 (CoQ10)
coffee fruit
cola nut
commiphora
cordyceps
creatine monohydrate
curcumen
Cynomorium
D-Ribose
deer root
deer velvet
Dendrobium
dextrates
dextrose
dragonhead
ecdysterone
egg
Egg protein
electrolytes blend (proprietary)
eleuthero
elk antler
ephedrine
Erodium cicutarium
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Eurycoma Longifolia
eurycomanone
folate
fungus
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garden cress
ginseng
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greens blend (proprietary)
guarana
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guayusa
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jiaogulan
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ketosterones
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lemongrass
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maca
macaenes
macamides
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malic acid
maral root
medium chain triglycerides (MCT)
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wheat germ
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Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Energy (lack of)

Table of Contents

Synopsis

Other ingredients used for Energy (lack of)

Other health conditions supported by coenzyme Q10 (CoQ10)

Products containing coenzyme Q10 (CoQ10)

Health Concerns

Brands

Evidence supporting the use of: Coenzyme Q10 (CoQ10)For the health condition: Energy (lack of)

Table of Contents

Synopsis

Other ingredients used for Energy (lack of)

Other health conditions supported by coenzyme Q10 (CoQ10)

Products containing coenzyme Q10 (CoQ10)

Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Energy (lack of)