Evidence supporting the use of: Higenamine
For the health condition: Energy (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Higenamine is a plant-derived alkaloid found in several traditional Chinese medicinal herbs, such as Nandina domestica and Aconitum species. Recent scientific interest has centered on its potential stimulant-like and cardiovascular effects, as higenamine acts as a beta-adrenergic receptor agonist. This mechanism is similar to other stimulants that may increase energy or alertness. Several small studies and in vitro experiments suggest that higenamine can increase heart rate and may promote lipolysis, which theoretically could enhance exercise performance and perceived energy. However, most of these studies are limited in size, scope, or are preclinical. Human trials directly measuring higenamine's effect on "energy" or fatigue are scarce, and those that exist typically evaluate related endpoints such as exercise capacity or metabolic rate rather than subjective energy levels.

While there is some mechanistic support and preliminary research indicating that higenamine may have stimulant-like properties, the overall quality and quantity of evidence is low. There is not enough robust clinical data to confidently support its use for general energy enhancement in healthy individuals. Regulatory agencies, including WADA, have banned higenamine for use in sport due to its potential performance-enhancing and cardiovascular effects, further highlighting its stimulant-like action. In summary, scientific support exists but is weak to moderate, and more rigorous clinical trials are needed.

More about Higenamine
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Other ingredients used for Energy (lack of)

7-Keto-DHEA
acai berry
acetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha d-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
aspartic acid
beta-alanine
biotin
black pepper
bасора
caffeine
capsaicinoids
coconut milk
coenzyme Q10 (CoQ10)
coffee fruit
cordyceps
creatine monohydrate
eleuthero
folate
fructose
ginseng
greens blend (proprietary)
guarana
guayusa
l-alanyl-l-glutamine
l-carnitine
l-glutamine
l-glycine
l-leucine
l-tyrosine
maca
magnesium
malic acid
maltodextrin
medium chain triglycerides (MCT)
microbial enzymes (proprietary)
milk
Acetyl-L-Tyrosine
nettle
pantothenic acid (vitamin B5)
pollen
protein
pyrroloquinoline disodium salt
rhodiola
rosemary
sage
shiitake mushroom
black ginger
sphaeranthus indicus
spirulina
succinic acid
tongkat ali
almond fruit
vegetable blend (proprietary)
velvet bean
vitamin B
vitamin B12
vitamin B6
whey protein
zinc
suma
jiaogulan
alpinia galangal
commiphora
bee pollen
lemongrass
siler root
cistanche
sweet flag
electrolytes blend (proprietary)
trace minerals
yerba mate
wheat germ
algae
1,3,7-Trimethylpurine-2,6-dione
Aralia
akebia
Alpha polylactate
Antler
Agastache
Arginine Creatine
Ardisia
Arginine malate
Anamu
Areca
adenosine triphosphate (ATP)
Algal protein
Amor seco
Arginine silicate
Atractylone
Animal protein
Beta Phenethylalamine
Blackthorn
Beta-hydroxybutyrate
Beef liver
Bovine Protein
berry
Ba Ji Tian
Borassus Palm
Borassus aethiopum
banana
Baobab
Borneol
Chia seed
Coconut
Cinnamomum
Coenzyme A
coconut oil
Codonopsis
Cynomorium
Catecholamine
Chlorophytum
Chuchuhuasi
Curcumen
Coca
Chicken
cola nut
Dendrobium
Deer Root
Deer Velvet
Dragonhead
Dextrates
D-Ribose
Dextrose
Erodium cicutarium
Egg
Elk antler
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Ephedrine
Egg protein
glucose
Ketone Salts
Milk Protein
peanut
Wheat

Products containing Higenamine

We currently have no products on Vitabase that contain this ingredient.