Evidence supporting the use of: L-glutamine
For the health condition: Energy (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-glutamine is an amino acid involved in several metabolic processes, including serving as a fuel source for rapidly dividing cells such as those in the immune and gastrointestinal systems. Its role in supporting energy, particularly in the context of "lack of energy" or fatigue, is an area of ongoing study. Scientific evidence primarily supports its use in specific clinical circumstances rather than general fatigue or low energy in healthy individuals. For example, glutamine supplementation has been shown to benefit individuals under extreme physical stress, such as athletes during intense training, by supporting muscle recovery and reducing markers of muscle damage. Glutamine is also conditionally essential during periods of illness, injury, or metabolic stress, when endogenous production may not meet the body's increased needs. There is limited direct evidence supporting its efficacy as a general energy booster for otherwise healthy people experiencing fatigue. Some small studies suggest that glutamine may help reduce fatigue in cancer patients undergoing chemotherapy or after major surgery, but these findings are not robust or widely replicated. Overall, while there is a biochemical rationale for glutamine’s involvement in energy metabolism—particularly in the context of stress or illness—current scientific validation for its use to treat general "lack of energy" is weak. Thus, glutamine should not be regarded as a primary intervention for boosting energy in the general population.

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Other ingredients used for Energy (lack of)

1,3,7-Trimethylpurine-2,6-dione
7-Keto-DHEA
Acai berry
Acetyl L-carnitine
Acetyl-L-Tyrosine
adenosine 5-triphosphate disodium (ATP)
Adenosine triphosphate (ATP)
Agastache
Akebia
Algae
Algal protein
Almond fruit
Alpha D-ribofuranose
Alpha polylactate
alpha-ketoglutarate (AKG)
alpinia galangal
amino acids
Amor seco
anamu
animal protein
antler
Aralia
Ardisia
Areca
arginine creatine
Arginine malate
Arginine silicate
ashwagandha
aspartic acid
atractylone
ba ji tian
banana
baobab
bee pollen
Beef liver
berry
beta phenethylalamine
beta-alanine
beta-hydroxybutyrate
biotin
black ginger
black pepper
blackthorn
Borassus aethiopum
borassus palm
borneol
bovine protein
bасора
caffeine
capsaicinoids
catecholamine
chia seed
Chlorophytum
chuchuhuasi
Cinnamomum
cistanche
coca
coconut
coconut milk
coconut oil
Codonopsis
Coenzyme A
coenzyme Q10 (CoQ10)
coffee fruit
cola nut
commiphora
cordyceps
creatine monohydrate
curcumen
Cynomorium
D-Ribose
deer root
deer velvet
Dendrobium
dextrates
dextrose
dragonhead
ecdysterone
egg
Egg protein
electrolytes blend (proprietary)
eleuthero
elk antler
ephedrine
Erodium cicutarium
Ethyl-Alpha-Guanido-Methyl-Ethanoate
Eurycoma Longifolia
eurycomanone
folate
fungus
gamma-butyrobetaine
garden cress
ginseng
glucose
GMS-ribose
greens blend (proprietary)
guarana
Guaranine
guayusa
Herb Robert
Higenamine
Ilex
jiaogulan
jungli-bean
ketone salts
ketosterones
kola nut
L-alanyl-L-glutamine
l-carnitine
L-glutamine
L-glycine
L-leucine
l-tyrosine
lemongrass
lipids
maca
macaenes
macamides
magnesium
malic acid
maral root
medium chain triglycerides (MCT)
Methylliberine
Microbial enzymes (proprietary)
Milk
Milk Protein
Ming Dang Shen
Mushroom
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Orchis latifolia
ornithine L-aspartic acid
Oroxylum indicum
Osha
oxaloacetic acid
pantothenic acid (vitamin B5)
paraxanthine
peanut
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pollen
Polygonatum
protein
Pseudostellaria
pyrroloquinoline disodium salt
pyrroloquinoline quinone
Rhodiola
ribose
robusta coffee
rosemary
Rubia yunnanensis
Rubiaceae
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sage
Sarivan
shiitake mushroom
Sichuan Lovage
Sida cordifolia
siler root
Southern Tsangshu
Sphaeranthus indicus
spirulina
succinic acid
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suma
sweet flag
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Theobromine
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trace minerals
Trichilia catigua
Trichopus zeylanicus
vegetable blend (proprietary)
velvet bean
vitamin B
vitamin B12
vitamin B6
Wheat
wheat germ
Whey protein
Wulinshen
Yerba mate
Yuzu
Zedoary
Zinc
Zingiberene

Products containing L-glutamine

Douglas Laboratories 5-HTP Plus Formula
Designs For Health Amino-D-Tox™
Designs For Health Amino-D-Tox™
Pure Encapsulations Amino-NR
Pure Encapsulations Amino Replete
Designs For Health BCAA Powder with L-Glutamine
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus pH
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Integrative Therapeutics Detoxication Factors
Integrative Therapeutics Detoxication Factors
Thorne EnteroMend NSF
Pure Encapsulations EpiIntegrity
Pure Encapsulations G.I. Fortify
Pure Encapsulations G.I. Fortify
Pure Encapsulations G.I. Integrity
Pure Encapsulations G.I. Integrity
Designs For Health GI Revive®
Designs For Health GI Revive®
Metagenics GI Sustain™ Powder
Metagenics Glutagenics® powder
Integrative Therapeutics Glutamine Forte Drink Mix
Vitabase HGH Complex
Designs For Health IBSynergy™
Klean Athlete Klean Essential Aminos + HMB®
Klean Athlete Klean Isolate ™
Thorne L-Glutamine
Pure Encapsulations l-Glutamine
Designs For Health L-Glutamine
Douglas Laboratories L-Glutamine
Pure Encapsulations l-Glutamine 500 mg
Pure Encapsulations l-Glutamine 850 mg
Pure Encapsulations l-Glutamine 850 mg
Designs For Health L-Glutamine Powder
Designs For Health L-Glutamine Powder
Douglas Laboratories L-Glutamine Powder
Thorne L-Glutamine Powder NSF
Pure Encapsulations Liver G.I. Detox
Thorne MediClear Plus
Integrative Therapeutics Multiplex-1 No-Iron
Douglas Laboratories Muscle Protect™ with HMB®
Designs For Health Neurolink™
Integrative Therapeutics Nutrivitamin No-Iron
Pure Encapsulations PureBi•Ome™ G.I.
Metagenics Ultra Potent-C 1000
Metagenics Ultra Potent-C Chewable
Metagenics UltraClear Plus® Detox Powder
Metagenics UltraClear Plus Detox Powder Berry
Metagenics UltraClear Plus Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Vanilla
Metagenics UltraClear RENEW Detox Powder Berry
Metagenics UltraClear RENEW Detox Powder Chai
Metagenics UltraClear RENEW Detox Powder Vanilla
Pure Encapsulations UltraDetox 10-Day Pure Pack
Metagenics UltraGI Replenish® Chocolate
Metagenics UltraGI Replenish Chocolate
Metagenics UltraGI Replenish Vanilla
Metagenics UltraGI Replenish Vanilla
Metagenics UltraInflamX Plus 360°® Chocolate/Orange
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Orange
Metagenics UltraInflamX Plus 360° Original Spice
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraInflamX Plus 360° Pineapple/Banana