Relationship: Energy (lack of) and l-glycine

Evidence supporting the use of: L-glycine
For the health condition: Energy (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-glycine is an amino acid with several physiological roles, including serving as a building block for proteins, participating in neurotransmission, and being involved in the synthesis of compounds like creatine and glutathione. There is emerging scientific interest in glycine’s potential to support energy levels, primarily through its roles in mitochondrial function and sleep quality rather than direct energy production. Some human and animal studies suggest glycine supplementation may improve sleep quality and reduce fatigue, which can indirectly enhance perceived daytime energy. For example, a few small clinical trials have demonstrated that glycine taken before bedtime can improve subjective sleep quality and reduce feelings of fatigue in healthy adults. Additionally, glycine’s involvement in the synthesis of creatine—an important molecule for cellular energy in muscle—suggests a possible mechanism for supporting energy metabolism.

However, robust evidence directly linking glycine supplementation to increased energy levels or treatment of chronic fatigue is limited. Most studies are small-scale, short-term, and focus on sleep or cognitive function rather than direct measures of energy. There is no large-scale clinical evidence to strongly support glycine as a primary therapy for low energy. Thus, while there is some scientific rationale and preliminary evidence, it remains modest, warranting a rating of 2 out of 5.

More about l-glycine
More about Energy (lack of)

Other ingredients used for Energy (lack of)

7-Keto-DHEA
acai berry
acetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha d-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
aspartic acid
beta-alanine
biotin
black pepper
bасора
caffeine
capsaicinoids
coconut milk
coenzyme Q10 (CoQ10)
coffee fruit
cordyceps
creatine monohydrate
eleuthero
folate
fructose
ginseng
greens blend (proprietary)
guarana
guayusa
l-alanyl-l-glutamine
l-carnitine
l-glutamine
l-glycine
l-leucine
l-tyrosine
maca
magnesium
malic acid
maltodextrin
medium chain triglycerides (MCT)
microbial enzymes (proprietary)
milk
Acetyl-L-Tyrosine
nettle
pantothenic acid (vitamin B5)
pollen
protein
pyrroloquinoline disodium salt
rhodiola
rosemary
sage
shiitake mushroom
black ginger
sphaeranthus indicus
spirulina
succinic acid
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almond fruit
vegetable blend (proprietary)
velvet bean
vitamin B
vitamin B12
vitamin B6
whey protein
zinc
suma
jiaogulan
alpinia galangal
commiphora
bee pollen
lemongrass
siler root
cistanche
sweet flag
electrolytes blend (proprietary)
trace minerals
yerba mate
wheat germ
algae
1,3,7-Trimethylpurine-2,6-dione
Aralia
akebia
Alpha polylactate
Antler
Agastache
Arginine Creatine
Ardisia
Arginine malate
Anamu
Areca
adenosine triphosphate (ATP)
Algal protein
Amor seco
Arginine silicate
Atractylone
Animal protein
Beta Phenethylalamine
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Beta-hydroxybutyrate
Beef liver
Bovine Protein
berry
Ba Ji Tian
Borassus Palm
Borassus aethiopum
banana
Baobab
Borneol
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Coconut
Cinnamomum
Coenzyme A
coconut oil
Codonopsis
Cynomorium
Catecholamine
Chlorophytum
Chuchuhuasi
Curcumen
Coca
Chicken
cola nut
Dendrobium
Deer Root
Deer Velvet
Dragonhead
Dextrates
D-Ribose
Dextrose
Erodium cicutarium
Egg
Elk antler
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Ecdysterone
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Egg protein
glucose
Ketone Salts
Milk Protein
peanut
Wheat

Other health conditions supported by l-glycine

Anxiety
Anxiety Disorders
Athletic and Exercise Aids
Autoimmune Disorders
Body Building
Cardiovascular Disease
Chemotherapy (reducing side effects)
Convalescence
Cuts
Depression
Diabetes
Energy (lack of)
Exercise
Fatigue
Free Radical Damage
Gastritis

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Evidence supporting the use of: L-glycine
For the health condition: Energy (lack of)

Table of Contents

Synopsis

Other ingredients used for Energy (lack of)

Other health conditions supported by l-glycine

Products containing l-glycine

Health Concerns

Brands

Evidence supporting the use of: L-glycineFor the health condition: Energy (lack of)

Table of Contents

Synopsis

Other ingredients used for Energy (lack of)

Other health conditions supported by l-glycine

Products containing l-glycine

Evidence supporting the use of: L-glycine
For the health condition: Energy (lack of)