The use of Pseudostellaria (commonly referred to as "Tai Zi Shen" in Traditional Chinese Medicine, or TCM) to support or treat lack of energy is justified primarily by tradition. In TCM, Pseudostellaria is categorized as a mild tonic for "Qi deficiency," which is often associated with fatigue, weakness, and general lack of vitality. It is considered gentler than other major Qi tonics like ginseng, and is traditionally recommended for those who are constitutionally weaker or for children. Classical TCM texts describe its ability to "tonify the middle and augment the Qi" and to "generate fluids and nourish Yin," making it suitable for symptoms such as tiredness, poor appetite, and thirst.

Scientific research on Pseudostellaria for treating fatigue or supporting energy is limited and mostly preclinical. Some animal studies have suggested immunomodulatory and adaptogenic effects, but robust clinical trials in humans are lacking. As such, while its use for energy support is deeply rooted in traditional practice, modern scientific validation is currently insufficient. The traditional evidence warrants a moderate evidence rating (2 out of 5), mainly due to its long-standing and widespread use within herbal medicine systems, rather than strong clinical research.