Evidence supporting the use of: Rhodiola
For the health condition: Energy (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Rhodiola rosea is an adaptogenic herb traditionally used in Russia, Scandinavia, and other parts of Europe to combat fatigue and enhance physical and mental performance. Modern scientific studies have investigated its effects on energy, particularly in relation to fatigue and physical endurance. Several randomized, placebo-controlled trials suggest that rhodiola supplementation may help reduce symptoms of fatigue, particularly in situations of stress, sleep deprivation, or intense mental demand. For example, a 2012 meta-analysis published in Phytomedicine reviewed 11 clinical trials and found that rhodiola showed potential benefits for physical and mental fatigue, though the authors noted that many studies had methodological limitations and small sample sizes.

Mechanistically, rhodiola is believed to influence stress response pathways, including modulation of cortisol levels and support of cellular energy metabolism through effects on mitochondrial function. While the evidence base is promising, it is not yet definitive. Larger, high-quality studies are needed to confirm its efficacy and determine optimal dosages. Importantly, most reported side effects are mild and transient. In summary, rhodiola has both a traditional and a growing scientific basis for supporting energy and combating fatigue, though the strength of the scientific evidence is currently moderate.

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