Evidence supporting the use of: Theobromine
For the health condition: Energy (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Theobromine is a naturally occurring alkaloid found primarily in cocoa beans and chocolate. It shares structural similarities with caffeine and is classified as a methylxanthine. Theobromine has mild stimulant effects, though its potency is notably less than that of caffeine. Scientific studies have demonstrated that theobromine can increase alertness, improve mood, and reduce fatigue, but these effects are generally weaker compared to caffeine. The mechanism involves antagonism of adenosine receptors, leading to increased neuronal activity and the release of stimulating neurotransmitters. While theobromine has a history of use in chocolate and traditional beverages like cacao, its primary use for "energy" or combating lack of energy is more recent and is based largely on its pharmacological similarity to caffeine. Clinical evidence supporting the use of theobromine specifically for energy enhancement is limited. Most studies focus on its cardiovascular effects, mood modulation, or its role in cough suppression. Studies that do address stimulation report mild increases in alertness and wakefulness, but generally not to a degree considered robust for treating significant fatigue or low energy. In summary, scientific evidence indicates a mild stimulant effect of theobromine, but the effect size and quality of evidence are moderate to low. It is less effective than caffeine, and while it may provide some benefit for mild energy support, it is not strongly validated for this purpose.

More about Theobromine
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Other ingredients used for Energy (lack of)

7-Keto-DHEA
acai berry
acetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha d-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
aspartic acid
beta-alanine
biotin
black pepper
bасора
caffeine
capsaicinoids
coconut milk
coenzyme Q10 (CoQ10)
coffee fruit
cordyceps
creatine monohydrate
eleuthero
folate
fructose
ginseng
greens blend (proprietary)
guarana
guayusa
l-alanyl-l-glutamine
l-carnitine
l-glutamine
l-glycine
l-leucine
l-tyrosine
maca
magnesium
malic acid
maltodextrin
medium chain triglycerides (MCT)
microbial enzymes (proprietary)
milk
Acetyl-L-Tyrosine
nettle
pantothenic acid (vitamin B5)
pollen
protein
pyrroloquinoline disodium salt
rhodiola
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sage
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sphaeranthus indicus
spirulina
succinic acid
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almond fruit
vegetable blend (proprietary)
velvet bean
vitamin B
vitamin B12
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whey protein
zinc
suma
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commiphora
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lemongrass
siler root
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electrolytes blend (proprietary)
trace minerals
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algae
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adenosine triphosphate (ATP)
Algal protein
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Atractylone
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berry
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cola nut
Dendrobium
Deer Root
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Products containing Theobromine

We currently have no products on Vitabase that contain this ingredient.