Evidence supporting the use of: American Wormseed
For the health condition: Enteritis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

American Wormseed (Dysphania ambrosioides, formerly Chenopodium ambrosioides) has a long history of use in traditional medicine, particularly in the Americas, as an anthelmintic (for expelling intestinal worms) and for various digestive complaints. Its use in supporting or treating enteritis (inflammation of the intestine) is primarily based on traditional practices rather than modern scientific validation. Historical ethnobotanical records note its employment for gastrointestinal problems, including symptoms that overlap with enteritis, such as abdominal pain and diarrhea. The primary active compounds, such as ascaridole, have demonstrated anti-parasitic and some antimicrobial activity in vitro. However, there is a lack of robust clinical trials or modern pharmacological studies directly evaluating its efficacy or safety for the treatment of enteritis specifically. Most references to its use for enteritis are anecdotal or appear in traditional herbal formularies. It is important to note that the plant and its essential oil can be toxic at higher doses, leading to significant adverse effects. In summary, while American Wormseed has traditional use in digestive and intestinal disorders (including those with symptoms similar to enteritis), the scientific evidence directly supporting its use for enteritis is limited, and any use should be approached with caution due to potential toxicity.

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