Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Microbial enzymes—such as proteases, lipases, and amylases derived from bacteria or fungi—are increasingly used to support digestive health, including conditions like enteritis. Enteritis involves inflammation of the small intestine, often resulting in malabsorption and digestive disturbances. Scientific evidence suggests that supplementation with microbial enzymes can help by compensating for impaired endogenous enzyme activity in the inflamed gut, thereby improving nutrient digestion and reducing the burden on the gastrointestinal tract.

Several clinical and preclinical studies have indicated that exogenous enzyme preparations (including microbial sources) may reduce gastrointestinal symptoms such as bloating, diarrhea, and malabsorption in various digestive disorders. For example, enzyme supplementation has demonstrated efficacy in improving nutrient absorption in patients with pancreatic insufficiency and in certain inflammatory bowel diseases, which share pathophysiological features with enteritis. Some animal studies specifically show that microbial enzyme supplementation can reduce markers of intestinal inflammation and improve gut barrier function.

However, while these findings are promising, direct evidence specifically targeting enteritis in humans is limited, and most of the data are extrapolated from related gastrointestinal conditions. Clinical guidelines do not routinely recommend microbial enzymes as a primary treatment for enteritis, but they may be considered as adjunctive support in cases of compromised digestion. More robust, targeted research is needed to fully validate their effectiveness for this specific indication.

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Integrative Therapeutics Lipase Concentrate