The use of Albizia species (such as Albizia lebbeck and Albizia julibrissin) for epilepsy is primarily supported by traditional medicine practices rather than robust scientific evidence. In Ayurvedic and various Asian traditional medicine systems, Albizia bark, leaves, or flowers have been used for neurological conditions, including as a calming agent for nervous disorders and in some cases for epilepsy or seizure-like symptoms. Several ethnobotanical surveys and historical texts mention the use of Albizia preparations as adjuncts in the management of convulsions, often in combination with other herbs.

However, scientific validation is limited. A few preclinical studies in animal models have suggested potential anticonvulsant effects of Albizia extracts—possibly through GABAergic or antioxidant pathways—but these findings are preliminary, and there are no well-controlled human clinical trials evaluating its efficacy or safety for epilepsy. The active constituents believed to be responsible include saponins, flavonoids, and alkaloids, but their mechanisms remain speculative.

In summary, while Albizia is recognized in traditional medicine for its calming and nervine properties and has been used for epilepsy in such contexts, scientific evidence supporting its efficacy is weak and mostly limited to animal studies. Therefore, Albizia’s use in epilepsy is best characterized as traditional, with low-level supporting evidence.