Evidence supporting the use of: Broussonetia
For the health condition: Epilepsy

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Broussonetia, particularly Broussonetia papyrifera (paper mulberry), has a history of use in traditional medicine systems, notably in East Asia. In some traditional Chinese medicine (TCM) texts, parts of the plant (such as roots or bark) have been incorporated into herbal formulations for neurological conditions, including epilepsy (referred to as "dian xian" in TCM). The rationale in these traditions often relates to harmonizing or calming the "wind" within the body, a concept believed to influence seizure activity. However, these traditional uses are often based on empirical observations and are not grounded in modern pharmacological understanding.

Despite its occasional use in traditional practices, there is very limited scientific evidence to support the efficacy or safety of Broussonetia species for epilepsy. Published biomedical literature and clinical trials are lacking; there are no robust animal or human studies directly investigating its anticonvulsant effects. The rating reflects that while traditional use exists and is documented, the scientific support is minimal or absent, and modern medical guidelines do not recognize Broussonetia as a treatment for epilepsy.

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