Evidence supporting the use of: Peony (unspecified)
For the health condition: Epilepsy

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Peony, particularly species such as Paeonia lactiflora, has a long history of use in traditional medicine systems, including Traditional Chinese Medicine (TCM), where it is known as "Bai Shao." In historical and folk medicine, peony root has been used to "calm the liver," "alleviate wind," and treat convulsions or spasms, which sometimes included conditions resembling epilepsy. The ancient Greeks and Romans also attributed antispasmodic properties to peony. For instance, Dioscorides and Pliny the Elder mentioned its use for treating seizures, especially in children.

Despite these traditional uses, there is little to no robust scientific validation for peony's efficacy in treating epilepsy. Modern pharmacological studies have identified compounds in peony (such as paeoniflorin) with neuroprotective and anti-inflammatory effects, but direct evidence from clinical trials or rigorous preclinical epilepsy models is lacking. Reviews of herbal treatments for epilepsy mention peony primarily in the context of its historical use rather than as a scientifically supported intervention. Therefore, the use of peony for epilepsy is best characterized as traditional, with very limited scientific support.

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