Carbohydrates play a scientifically validated role in supporting the effects of the epinephrine (adrenaline) system in the human body, particularly during periods of stress, exercise, or hypoglycemia. Epinephrine, a hormone released by the adrenal medulla, stimulates several metabolic pathways, most notably increasing blood glucose levels to provide immediate energy. This is achieved by promoting glycogenolysis (the breakdown of glycogen to glucose) and gluconeogenesis (the creation of new glucose). Carbohydrate intake is essential in maintaining sufficient glycogen stores in the liver and muscles, enabling the body to respond effectively to epinephrine signals.

Multiple clinical studies demonstrate that carbohydrate ingestion before or during physical activity enhances performance and recovery by sustaining blood glucose levels and delaying fatigue, both processes heavily mediated by catecholamines like epinephrine. In cases of hypoglycemia (low blood sugar), which can trigger a strong epinephrine response, rapid carbohydrate consumption is the first-line intervention, underscoring its physiological relevance.

While carbohydrates are not "supporting" epinephrine in the sense of increasing its production, they are critical for enabling the body to respond to epinephrine’s metabolic effects. Overall, the scientific literature robustly supports the functional relationship between dietary carbohydrate and the physiological actions of epinephrine.