Evidence supporting the use of: Ephedra
For the body system: Epinephrine

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Ephedra, also known as Ma Huang, is a plant that contains the active compounds ephedrine and pseudoephedrine. These compounds are sympathomimetic amines, which means they stimulate the sympathetic nervous system—the same system activated by epinephrine (adrenaline). Ephedrine acts on adrenergic receptors, increasing heart rate, dilating bronchi, raising blood pressure, and stimulating the central nervous system, closely mirroring the physiological effects of endogenous epinephrine. Historically, Ephedra has been used in traditional Chinese medicine for thousands of years to treat asthma, bronchitis, and other respiratory conditions, all of which are influenced by epinephrine-mediated pathways.

From a scientific perspective, numerous studies have confirmed that ephedrine and related alkaloids from Ephedra exert pharmacological effects by stimulating adrenergic receptors, leading to increased release and decreased reuptake of norepinephrine and, to a lesser extent, epinephrine. This action underpins the use of Ephedra-containing products as decongestants, bronchodilators, and stimulants. However, due to significant safety concerns—including cardiovascular side effects and risk of stroke—ephedrine-containing supplements have been banned or restricted in many countries.

In summary, there is robust scientific evidence supporting the use of Ephedra to stimulate the epinephrine (adrenergic) body system, although modern clinical use is limited due to potential adverse effects.

More about Ephedra
More about Epinephrine

Products containing Ephedra

We currently have no products on Vitabase that contain this ingredient.