Evidence supporting the use of: Black cohosh
For the body system: Estrogen

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Black cohosh (Actaea racemosa) is commonly used to support the estrogen body system, particularly for alleviating symptoms associated with menopause, such as hot flashes, night sweats, and mood changes. The use of black cohosh in this context is both traditional (used by Native Americans and in European herbal medicine) and supported by some scientific research, though the quality and consistency of evidence vary. Several randomized controlled trials and meta-analyses have investigated its effects on menopausal symptoms. Some studies suggest that black cohosh may have a modest effect in reducing hot flashes and other vasomotor symptoms, but results are mixed, with other studies showing no significant benefit over placebo. The mechanism of action is not fully understood; black cohosh does not appear to contain phytoestrogens or directly increase estrogen levels but may act via serotonergic pathways or have an effect on other neurotransmitters.

Systematic reviews, including those by the Cochrane Collaboration, conclude that while black cohosh may offer mild benefit for menopausal symptoms, the evidence is not robust enough to recommend it as a first-line therapy. Safety concerns are minimal for short-term use, but there have been rare reports of liver toxicity. Overall, the use of black cohosh for supporting the estrogen body system is based on moderate scientific evidence, but further high-quality research is needed to clarify its efficacy and safety profile.

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