Evidence supporting the use of: Bugbane
For the body system: Estrogen
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Bugbane, commonly known as black cohosh (Actaea racemosa or formerly Cimicifuga racemosa), has a long history of use in traditional medicine for supporting women’s health, particularly in alleviating symptoms associated with menopause, such as hot flashes and night sweats. The rationale for using black cohosh to support the estrogen body system stems from its perceived ability to address estrogen deficiency symptoms, though it does not actually contain phytoestrogens or estrogen itself.
Scientific validation comes from several randomized controlled trials and meta-analyses, which have investigated black cohosh's effectiveness for menopausal symptoms. Some studies, such as those summarized in a 2012 Cochrane review, found modest benefit in reducing vasomotor symptoms compared to placebo, though results are mixed and not all clinical trials have shown effectiveness. The mechanism of action remains unclear; black cohosh does not appear to increase estrogen levels or bind to estrogen receptors, but may exert effects via serotonergic pathways or other neuroendocrine mechanisms.
Overall, black cohosh (bugbane) is supported by both tradition and scientific research, but scientific evidence is moderate (rated 3/5) due to inconsistent results and gaps in understanding its mode of action. Major guidelines, such as those from North American Menopause Society, acknowledge its potential utility, but call for further research and caution in certain populations (e.g., those with hormone-sensitive conditions).
Other ingredients that support Estrogen
7-hydroxymatairesinol (HMR)black cohosh
chaste tree
d-glucarate
daidzin
dandelion
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
fennel
flaxseed
genistein
genistin
ginseng
HMR lignan
hops
indole-3-carbinol
licorice root
lignans
maca
sage
secoisolariciresinol diglucoside
soybean
spearmint leaf
vitamin B6
vitamin E
wild yam
red clover
anise
yarrow
dioscorea
Equol (proprietary)
soy isoflavones
27-deoxyactein
4-Hydroxyandrostenedione
8-Prenylnaringenin
Agnuside
Anti-aromatase
Brassica
Bugbane
biochanin
Barbasco
Cohosh
Clary sage
Cruciferous
Casticin
Coumesterol
DHEA
Daidzein
Dong Quai
Diosgenin
Isoflavones
Soy Protein
Other body systems supported by Bugbane
EstrogenFemale Reproductive System
Joints
Nerves
Ovaries
Reproductive System
Uterus