Evidence supporting the use of: Bugbane
For the body system: Estrogen

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bugbane, commonly known as black cohosh (Actaea racemosa or formerly Cimicifuga racemosa), has a long history of use in traditional medicine for supporting women’s health, particularly in alleviating symptoms associated with menopause, such as hot flashes and night sweats. The rationale for using black cohosh to support the estrogen body system stems from its perceived ability to address estrogen deficiency symptoms, though it does not actually contain phytoestrogens or estrogen itself.

Scientific validation comes from several randomized controlled trials and meta-analyses, which have investigated black cohosh's effectiveness for menopausal symptoms. Some studies, such as those summarized in a 2012 Cochrane review, found modest benefit in reducing vasomotor symptoms compared to placebo, though results are mixed and not all clinical trials have shown effectiveness. The mechanism of action remains unclear; black cohosh does not appear to increase estrogen levels or bind to estrogen receptors, but may exert effects via serotonergic pathways or other neuroendocrine mechanisms.

Overall, black cohosh (bugbane) is supported by both tradition and scientific research, but scientific evidence is moderate (rated 3/5) due to inconsistent results and gaps in understanding its mode of action. Major guidelines, such as those from North American Menopause Society, acknowledge its potential utility, but call for further research and caution in certain populations (e.g., those with hormone-sensitive conditions).

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