Evidence supporting the use of: Flaxseed
For the body system: Estrogen

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flaxseed is scientifically investigated for its effect on the estrogen body system due to its high content of lignans, a type of phytoestrogen. Phytoestrogens are plant-derived compounds that can mimic or modulate the action of estrogen in the body. Several clinical studies and meta-analyses have examined the impact of flaxseed and its lignans on hormone balance, particularly in women. Evidence suggests that flaxseed consumption may modestly influence estrogen metabolism, potentially increasing the ratio of 2-hydroxyestrone to 16α-hydroxyestrone, which is considered a favorable change regarding estrogen-sensitive conditions.

Some research points to the possible benefits of flaxseed in reducing menopausal symptoms such as hot flashes, although results are mixed and generally less robust compared to conventional hormone therapy. Additionally, observational and small interventional studies have suggested that flaxseed may have a protective effect against hormone-dependent cancers, such as breast cancer, possibly due to its weak estrogenic and anti-estrogenic effects.

However, the evidence is not unequivocal, and the effects of flaxseed on estrogen levels and related conditions can vary based on individual differences and dosages. While there is a credible scientific rationale and some supporting evidence for the use of flaxseed in supporting the estrogen body system, more large-scale and long-term clinical trials are needed to establish its efficacy with higher certainty.

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