Evidence supporting the use of: Lignan
For the body system: Estrogen

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lignans are a group of polyphenolic compounds found in plants such as flaxseed, sesame seeds, and whole grains. They are considered phytoestrogens, meaning they can exert weak estrogen-like effects in the body by binding to estrogen receptors. Scientific studies have investigated the impact of dietary lignans on estrogen metabolism and their potential to modulate estrogenic activity, particularly in women. Research shows that lignans can be converted by intestinal bacteria into enterolignans (enterodiol and enterolactone), which have been observed to influence the balance of estrogen metabolites in the human body. Some epidemiological studies suggest that higher intake of lignan-rich foods may be associated with a reduced risk of hormone-dependent cancers, such as breast cancer, and may help alleviate mild menopausal symptoms. However, clinical evidence is mixed and often limited by small sample sizes and short study durations.

Overall, there is moderate scientific support for the use of lignans to support the estrogen body system, particularly with respect to maintaining estrogen balance and possibly reducing the risk of estrogen-related conditions. However, more robust, large-scale randomized controlled trials are needed to establish definitive efficacy and optimal dosing.

More about Lignan
More about Estrogen

Other body systems supported by Lignan

Breasts
Estrogen
Female Reproductive System
Heart
Prostate

Products containing Lignan

We currently have no products on Vitabase that contain this ingredient.