Evidence supporting the use of: Miroestrol
For the body system: Estrogen
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Miroestrol is a phytoestrogenic compound isolated from the plant Pueraria mirifica, which has a long history of traditional use in Thailand and neighboring countries for promoting female vitality, breast enlargement, and alleviating menopausal symptoms. The traditional rationale for its use is based on the belief that the plant’s estrogen-like properties can help support the female endocrine system, particularly estrogenic functions. While laboratory studies have confirmed that miroestrol and related compounds can bind to estrogen receptors and exert weak estrogenic activity in vitro and in animal models, robust clinical evidence in humans is lacking. Most published studies are either small, preliminary, or have methodological limitations. As such, the use of miroestrol to support the estrogen body system is primarily justified by traditional use rather than by strong scientific validation. Reports of its benefits are largely anecdotal or based on traditional practices rather than on large, well-controlled clinical trials. Regulatory agencies do not officially recognize miroestrol as an approved treatment for estrogen-related conditions. Therefore, while there is a historical basis for its use, the scientific evidence remains limited and inconclusive.
Other ingredients that support Estrogen
7-hydroxymatairesinol (HMR)black cohosh
chaste tree
d-glucarate
daidzin
dandelion
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dong quai root
fennel
flaxseed
genistein
genistin
ginseng
HMR lignan
hops
indole-3-carbinol
licorice root
lignans
maca
sage
secoisolariciresinol diglucoside
soybean
spearmint leaf
vitamin B6
vitamin E
wild yam
red clover
anise
yarrow
dioscorea
Equol (proprietary)
soy isoflavones
27-deoxyactein
4-Hydroxyandrostenedione
8-Prenylnaringenin
Agnuside
Anti-aromatase
Brassica
Bugbane
biochanin
Barbasco
Cohosh
Clary sage
Cruciferous
Casticin
Coumesterol
DHEA
Daidzein
Dong Quai
Diosgenin
Isoflavones
Soy Protein
Other body systems supported by Miroestrol
BreastsEstrogen
Female Reproductive System
Reproductive System
Uterus
Vagina