Evidence supporting the use of: Vitex Agnus-Castus
For the health condition: Estrogen (low)
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Vitex agnus-castus (chaste tree) has a long history of traditional use for various female reproductive concerns, including menstrual irregularities and symptoms related to hormonal imbalances. Historically, it has been employed to support conditions perceived to be related to low estrogen, such as amenorrhea (absence of menstruation) and certain menopausal symptoms. The rationale in traditional herbal medicine is that Vitex may help "balance" hormones, though its specific action on estrogen levels remains unclear.
From a scientific perspective, Vitex primarily affects the pituitary gland by modulating prolactin secretion, which can indirectly influence other reproductive hormones, including estrogen and progesterone. However, current evidence does not robustly demonstrate that Vitex directly raises low estrogen levels. Clinical studies focus mainly on its efficacy in treating premenstrual syndrome (PMS) and cyclic mastalgia, with less direct investigation into its effects on hypoestrogenism. Thus, while there is a traditional basis for its use in supporting estrogen-related conditions, scientific validation specifically for raising low estrogen is limited, and the overall evidence quality is moderate at best.
In summary, the use of Vitex agnus-castus to treat or support low estrogen is rooted in traditional herbal practice, with only limited and indirect scientific support regarding its ability to impact estrogen specifically.
Other ingredients used for Estrogen (low)
black cohoshdong quai root
flaxseed
licorice root
soybean
vitamin D
wild yam
red clover
Equol (proprietary)
8-Prenylnaringenin
Cohosh
Dong Quai
Estrogen
Other health conditions supported by Vitex Agnus-Castus
AmenorrheaAnxiety
Breasts (swelling and tenderness)
Dysmenorrhea
Endometriosis
Estrogen (low)
Infertility
Menopause
Menorrhagia
Menstrual Irregularity
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
PMS Type S
Progesterone (low)
Sex Drive (low)