Evidence supporting the use of: Beta Hydroxybutyrate
For the health condition: Exercise
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Beta Hydroxybutyrate (BHB) is a ketone body produced naturally in the liver during periods of low carbohydrate availability, such as fasting or adherence to a ketogenic diet. In recent years, exogenous BHB supplements have been marketed for their potential to enhance exercise performance, particularly endurance activities. Scientific studies suggest that BHB supplementation can increase circulating ketone levels, providing an alternative energy substrate for muscles and the brain, which may help spare muscle glycogen and reduce perceived exertion during prolonged exercise.
Several small-scale clinical trials and animal studies have investigated the effects of exogenous ketones (including BHB) on exercise performance. Some research has demonstrated modest improvements in endurance performance, particularly in athletes already adapted to a ketogenic diet. However, results are mixed, with some studies showing no significant benefit and others indicating potential gastrointestinal discomfort or impaired exercise economy, especially in high-intensity, glycolytic activities.
Overall, while there is a plausible physiological basis and emerging scientific evidence for the use of BHB to support certain types of exercise (mainly endurance), the quality and consistency of evidence are moderate at best. Larger, well-controlled human trials are needed to clarify its efficacy and optimal application. Thus, BHB's use in exercise is scientifically investigated but not yet definitively proven or universally endorsed.
Other ingredients used for Exercise
acetyl l-carnitinebranched-chain amino acids
ashwagandha
beta-alanine
coenzyme Q10 (CoQ10)
cordyceps
creatine monohydrate
electrolytes blend (proprietary)
ginseng
l-citrulline
l-glutamine
magnesium
omega-3 fatty acids
spirulina
zinc
vitamin B12
1,3,7-Trimethylpurine-2,6-dione
Alpha polylactate
Alpha-ketoisocaproic acid
Arachidonic Acid
adenosine 5-triphosphate disodium (ATP)
Alpha hydroxyisocaproic acid
Arginine Creatine
Arginine pyroglutamate
Arginine silicate
BCAA
Beta-hydroxybutyrate
Arginine Alpha Ketoglutarate
astaxanthin
Bovine Protein
capsaicinoids
capsicum
Chia seed
colostrum
Dextrose
endo-peptidase
fructose
Ketone Salts
l-alanyl-l-glutamine
l-glycine
ornithine alpha-ketoglutarate
protease
protein
succinic acid
Other health conditions supported by Beta Hydroxybutyrate
Alzheimer's DiseaseCancer (natural therapy for)
Cardiovascular Disease
Depression
Dementia
Epilepsy
Exercise
Fatigue
Inflammation
Memory and Brain Function
Metabolic Syndrome
Migraine
Multiple Sclerosis
Parkinson's Disease
Seizures
Weight Loss
Energy (lack of)
Fat Metabolism (poor)
Inflammatory Bowel Disorders
Nerve Damage
Wasting