Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ornithine alpha-ketoglutarate (OKG) is sometimes used as a dietary supplement to support exercise performance and recovery. The rationale for its use is based on its role as a precursor in amino acid metabolism and its involvement in the urea cycle, which may help to reduce ammonia accumulation during intense physical activity. Some small-scale studies and animal research have suggested that OKG supplementation may help reduce muscle protein breakdown, improve nitrogen balance, and potentially enhance recovery after strenuous exercise. Additionally, OKG has been studied for its effects on wound healing and recovery from trauma, which has led to interest in its application for athletes or individuals undergoing intense physical training.

However, the scientific evidence supporting OKG’s effectiveness for exercise performance or recovery in healthy, athletic populations is limited and not robust. Most studies are either small, involve specific patient populations (such as burn victims or the elderly), or show only modest benefits. Systematic reviews and meta-analyses generally conclude that while OKG may have some potential in clinical settings for muscle wasting or severe trauma, evidence for its use in sports and exercise is weak. Therefore, while there is a plausible scientific rationale and some preliminary data, the quality and quantity of evidence are insufficient to strongly support its widespread use for exercise enhancement.

More about ornithine alpha-ketoglutarate
More about Exercise

Other ingredients used for Exercise

Other health conditions supported by ornithine alpha-ketoglutarate

Products containing ornithine alpha-ketoglutarate

Pure Encapsulations Growth Hormone Support
Vitabase HGH Complex