Evidence supporting the use of: Abrus
For the health condition: Eye Infections

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Abrus, commonly referring to Abrus precatorius (jequirity or rosary pea), has been traditionally used in some regions for the treatment of eye infections, particularly in South Asian and South American traditional medicine systems. Historical records and ethnobotanical surveys indicate the use of Abrus seeds or extracts—sometimes called "jequirity infusion"—as a topical remedy for ophthalmic conditions such as conjunctivitis and trachoma. This practice dates back to the late 19th and early 20th centuries, where jequirity infusion was used as an ocular irritant intended to provoke a healing inflammatory response in chronic eye infections. However, modern scientific evidence supporting its efficacy and safety is severely lacking, and there are significant safety concerns due to the presence of abrin, a highly toxic ribosome-inactivating protein found in the seeds. Reports of severe ocular toxicity, inflammation, and even vision loss following its use have been documented in medical literature. As a result, the use of Abrus for eye infections has been largely abandoned in favor of safer and more effective treatments. While its use is rooted in historical tradition, it is not supported by robust clinical trials or contemporary medical practice.

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