Divi-divi (Caesalpinia coriaria) is a plant native to Central and South America, and its pods and leaves have been used in traditional medicine for a variety of purposes. The use of divi-divi to support or treat eye infections appears to be primarily based on traditional practices in some cultures, rather than on solid scientific validation. In folk medicine, extracts or decoctions made from divi-divi pods or leaves have occasionally been applied as washes or compresses for eye complaints, including infections or inflammation. However, there is a lack of detailed ethnobotanical documentation specifying its widespread use specifically for eye infections, and the traditional use seems limited to certain geographic regions. From a scientific standpoint, there is currently little to no published research evaluating the efficacy or safety of divi-divi for eye infections in humans or animals. While some laboratory studies have reported that divi-divi contains tannins and other polyphenolic compounds with antibacterial or astringent properties, these findings are preliminary and do not directly support its application for ocular conditions. No clinical trials or robust pharmacological investigations have been conducted to substantiate its use for eye infections. Therefore, while there is some traditional precedent for using divi-divi in this manner, scientific evidence remains minimal.