Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Citrus bioflavonoids have a longstanding history of use in traditional and alternative medicine, particularly for supporting vascular health. Their application for eye problems, such as retinopathy or general eye health, traces back to the mid-20th century when researchers like Albert Szent-Györgyi, who discovered vitamin C, suggested bioflavonoids (sometimes called “vitamin P”) could support capillary resistance and integrity. Since the small blood vessels in the eyes are prone to damage from oxidative stress and inflammation, it was theorized that bioflavonoids, with their antioxidant and anti-inflammatory properties, might protect ocular health or help with issues like retinal hemorrhages or diabetic retinopathy.

However, robust scientific validation is limited. Some small clinical and animal studies have suggested that certain bioflavonoids (e.g., hesperidin, rutin) may reduce capillary fragility and oxidative damage, which are relevant to eye conditions. Yet, these studies are preliminary, and systematic reviews have not confirmed significant benefits for eye diseases in humans. Large-scale, well-controlled clinical trials are lacking.

Therefore, the use of citrus bioflavonoids for eye problems is primarily justified by tradition and historical precedent, with some biological plausibility, but only modest supporting evidence. The scientific consensus does not currently support their routine use for treating or preventing eye conditions, so the evidence rating is a 2 out of 5.

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Other ingredients used for Eye Problems

Other health conditions supported by citrus bioflavonoids

Products containing citrus bioflavonoids

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Vitabase Chewable Vitamin C
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Metagenics Echinacea Synergy
Designs For Health Electrolyte Synergy™
Douglas Laboratories Hair, Skin and Nails Plus
Vitabase Hair, Skin & Nails Formula
Pure Encapsulations Hair/Skin/Nails Ultra
Metagenics ImmuCore
Metagenics Immune Defense Pack
Integrative Therapeutics K-PAX MitoNutrients
Vitabase Life's Essentials Plus
Douglas Laboratories Malic Acid + Magnesium
Metagenics Multigenics®
Metagenics Multigenics Intensive Care
Metagenics Multigenics Intensive Care without Iron
Metagenics Multigenics without Iron
Douglas Laboratories Natural C
Integrative Therapeutics Nutrivitamin No-Iron
Metagenics PhytoMulti™ Multivitamin
Metagenics PhytoMulti With Iron
Metagenics PhytoMulti Without Iron
Metagenics PhytoMultivitamin
Designs For Health Primal Multi™
Pure Encapsulations PurePals
Pure Encapsulations PurePals with Iron
Vitabase Quercetin Plus
Designs For Health Stellar C™
Metagenics Ultra Potent-C 1000
Metagenics Ultra Potent-C 500
Metagenics Ultra Potent-C Chewable
Metagenics Ultra Potent-C Powder
Douglas Laboratories Ultra Preventive ® Kids Grape Flavor
Douglas Laboratories Ultra Preventive ® Kids Orange Flavor
Thorne Vitamin C With Flavonoids
Integrative Therapeutics Vitamin C with Quercetin
Metagenics Wellness Essentials Active Daily Packs