Self-Heal (Prunella vulgaris) has a long history of use in traditional herbal medicine, particularly in Europe and Asia. It has been referred to as "all-heal" or "heal-all" for its broad purported medicinal properties. In the context of eye health, traditional texts and folk medicine systems have sometimes used Self-Heal in poultices or washes for minor eye irritations, conjunctivitis, or inflammation. These uses are rooted in the plant's reputation for its anti-inflammatory and antimicrobial properties, which are well-documented in pre-modern herbal manuscripts and Materia Medica. However, the specific application for eye problems is less prominent than its use for wounds, mouth ulcers, or sore throats.

From a scientific perspective, there are very limited studies directly evaluating the efficacy or safety of Self-Heal for any eye condition in humans. Some laboratory research has shown that Prunella vulgaris extracts contain flavonoids, rosmarinic acid, and other polyphenols with anti-inflammatory and antioxidant effects. While these constituents could theoretically be beneficial for ocular inflammation or infection, there is currently no clinical trial data supporting its use for any specific eye disease. As such, the use of Self-Heal for eye problems is justified by tradition rather than by scientific validation.