Evidence supporting the use of: Vitamin A (retinyl palmitate)
For the health condition: Eye Problems

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin A, particularly in the form of retinyl palmitate, is scientifically validated for supporting and treating certain eye problems, especially those related to vitamin A deficiency. Vitamin A is essential for the formation of rhodopsin, a photopigment in the retina required for low-light (night) vision. Deficiency leads to night blindness and, in more severe cases, to xerophthalmia—a condition marked by dryness of the conjunctiva and cornea, which can progress to corneal ulceration and blindness if untreated. Supplementation with vitamin A reverses these symptoms and is a mainstay of therapy in populations at risk of deficiency, as endorsed by the World Health Organization (WHO) and numerous clinical studies.

Retinyl palmitate is a storage form of vitamin A commonly used in oral and injectable preparations. It is efficiently converted to active vitamin A in the body. The role of vitamin A in maintaining the integrity of ocular epithelial tissues and supporting the function of the conjunctiva and cornea is well documented. However, for non-deficiency-related eye diseases, such as age-related macular degeneration or glaucoma, evidence does not support the use of vitamin A supplementation unless the patient is deficient. In summary, there is robust scientific support—based on decades of clinical research and public health intervention—for the use of vitamin A (retinyl palmitate) in preventing and treating eye problems caused by deficiency.

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