Evidence supporting the use of: Anthocyanidins
For the body system: Eyes
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Anthocyanidins are a class of flavonoids found in many fruits and vegetables, notably in berries, red grapes, and purple corn. They are responsible for the vibrant red, purple, and blue pigments in these foods. Scientific research has explored their potential benefits for eye health, mainly due to their antioxidant and vascular-protective properties. Several studies suggest that anthocyanidins, especially those found in bilberry (Vaccinium myrtillus), may support visual function and protect against retinal damage by neutralizing free radicals and improving microcirculation in the ocular tissues.
Clinical trials, though limited in size and scope, have reported that anthocyanidin-rich extracts can improve night vision and reduce visual fatigue, particularly in individuals exposed to prolonged screen time or bright lights. The hypothesized mechanisms include strengthening the retinal capillaries, protecting photoreceptor cells, and modulating inflammatory pathways.
Despite these promising findings, large-scale, well-controlled human studies are still lacking, and most evidence is derived from animal models or small human trials. Thus, while there is scientific rationale and some preliminary clinical support for the use of anthocyanidins in eye health—especially for visual fatigue and retinal protection—the overall quality and consistency of evidence are moderate. Health authorities generally recognize their antioxidant benefits but have not approved them for the prevention or treatment of specific eye diseases.
Other ingredients that support Eyes
3,3'-dihydroxy-B-carotene-4,4'-dioneAcetyl L-carnitine
Alchornea
Algae
algal oil
Alpha-carotene
anchovies
anthocyanidins
anthocyanins
anthocyanosides
apricot
Aronia melanocarpa
astaxanthin
avocado
barbary matrimony vine
bee products
Beef liver
berry
beta-carotene
beta-zeacarotene
bilberry
bioflavonoids
black currant
blackberry
Blakeslea trispora
blueberry
broccoli
calamari oil
cantaloupe
capsanthin
Carnosine
carotene (unspecified)
carrot
Celosia
chickweed
Chinese Ligustrum berry
chrysanthemum
citicoline
cocklebur
cod liver oil
cornflower
Cornus
crocetin
crocin
Crypthecodinium
cryptoxanthin
currant
cyanidin
d-alpha tocopherol
DHA (docosahexaenoic acid)
docosahexaenoic Acid
Dunaliella
Dunaliella salina
egg
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
ergothioneine
Eyebright
Fagopyrum
fat liver oil
fatty acids
fibroblast growth factor
fish
fish oil
flavoglycosides
flavonoids
flavonols
fruit
fruit and vegetable blend (proprietary)
Gac
gamma-carotene
ginkgo flavone glycoside
Glutathione
goji berry
gooseberry
Haematococcus pluvialis
haliotis
herbal blend (proprietary)
huckleberry
hyaluronic acid
Idebenone
kale
L-carnosine
L-taurine
Ligustrum
lipids
lutein
Lycium
marigold
Marine fat
Marine lipid
Melatonin
Mineral ascorbate
mixed carotenoids
Morus
Mulberry
N-Acetyl Carnosine
Oligomeric proanthocyanidins
omega-3 fatty acids
orange
Phaffia rhodozyma
pine bark
Polygonum
polyphenols
polyunsaturated fat
proanthocyanidins
procyanidol
pumpkin
Pycnogenol
riboflavin (vitamin B2)
rose
rue
rutin
saffron
Salmon Oil
Schizochytrium
Schizochytrium Oil
Spanish Needle
spinach
Tagetes
Taurine
Tea
trace minerals
Triphala
Troxerutin
vegetable and fruit blend (proprietary)
vitamin A
vitamin B
vitamin C
vitamin E
Xanthophyll
Zeaxanthin
Zinc
Other body systems supported by anthocyanidins
ArteriesBlood
Brain
Capillaries
Circulatory System
Eyes
Gastrointestinal Tract
Heart
Immune System
Skin
Veins
