Evidence supporting the use of: Anthocyanidins
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Anthocyanidins are a class of flavonoids found in many fruits and vegetables, notably in berries, red grapes, and purple corn. They are responsible for the vibrant red, purple, and blue pigments in these foods. Scientific research has explored their potential benefits for eye health, mainly due to their antioxidant and vascular-protective properties. Several studies suggest that anthocyanidins, especially those found in bilberry (Vaccinium myrtillus), may support visual function and protect against retinal damage by neutralizing free radicals and improving microcirculation in the ocular tissues.

Clinical trials, though limited in size and scope, have reported that anthocyanidin-rich extracts can improve night vision and reduce visual fatigue, particularly in individuals exposed to prolonged screen time or bright lights. The hypothesized mechanisms include strengthening the retinal capillaries, protecting photoreceptor cells, and modulating inflammatory pathways.

Despite these promising findings, large-scale, well-controlled human studies are still lacking, and most evidence is derived from animal models or small human trials. Thus, while there is scientific rationale and some preliminary clinical support for the use of anthocyanidins in eye health—especially for visual fatigue and retinal protection—the overall quality and consistency of evidence are moderate. Health authorities generally recognize their antioxidant benefits but have not approved them for the prevention or treatment of specific eye diseases.

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Products containing anthocyanidins

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