Evidence supporting the use of: Anthocyanosides
For the body system: Eyes

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Anthocyanosides, also known as anthocyanins, are flavonoid compounds found in berries such as bilberry, blueberry, and black currant. Their use for eye health is supported by both traditional use—especially in European herbal medicine—and some scientific research, though the quality of evidence is limited. Historically, bilberry extracts rich in anthocyanosides were reputed to improve night vision, allegedly used by World War II pilots, though this anecdote lacks strong documentation.

Scientifically, anthocyanosides have antioxidant and anti-inflammatory properties, and some laboratory and animal studies suggest they may help protect retinal cells from oxidative stress. Small clinical trials have explored their effects on conditions like night vision, retinal health, and visual fatigue. Some studies show modest improvements in subjective visual symptoms or adaptation to darkness, but results are inconsistent and sample sizes are generally small. Systematic reviews and larger, well-controlled human studies are lacking, making it difficult to draw firm conclusions about efficacy.

Overall, while there is a plausible mechanistic basis and some preliminary clinical evidence for anthocyanosides supporting eye health, especially in relieving visual fatigue and possibly aiding night vision, the current body of evidence is not robust. Thus, the scientific evidence rating is 2 out of 5, indicating limited but suggestive data.

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