Evidence supporting the use of: Bioflavonoids (mixture)
For the body system: Eyes
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Bioflavonoids, also known as flavonoids, are a diverse group of phytonutrients found in many fruits and vegetables. They have been traditionally used to support vascular health, including the microvasculature of the eyes. Scientifically, bioflavonoids such as quercetin, rutin, and hesperidin have demonstrated antioxidant, anti-inflammatory, and capillary-strengthening properties in laboratory and animal studies. These effects are relevant to eye health because oxidative stress and microvascular dysfunction are implicated in the development of common ocular diseases, such as age-related macular degeneration (AMD), diabetic retinopathy, and cataracts. Some small human studies and observational data suggest that diets high in flavonoids may correlate with a reduced risk of certain eye conditions, particularly those involving microvascular damage or oxidative stress. For example, rutin and hesperidin have been shown to reduce capillary fragility, and quercetin has demonstrated protective effects on retinal cells in animal models. However, direct clinical evidence for the efficacy of bioflavonoid mixtures as a supplement for eye health in humans is limited and not conclusive. Overall, while there is a scientific rationale and some preliminary evidence supporting the use of bioflavonoids for eye health, large-scale randomized controlled trials in humans are lacking. Thus, the evidence is rated moderate (3/5), reflecting promising mechanisms and early data, but not strong clinical proof.
Other ingredients that support Eyes
acetyl l-carnitinealgal oil
alpha-carotene
anchovies
anthocyanins
apricot
astaxanthin
berry flavor
beta-carotene
bilberry
black currant
blackberry
blueberry
broccoli
calamari oil
carrot
citicoline
cryptoxanthin
d-alpha tocopherol
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
fish oil
flavonols
fruit and vegetable blend (proprietary)
gooseberry
hyaluronic acid
hypromellose
kale
l-carnosine
l-taurine
lutein
mackerel
mannitol
marine lipid
melatonin
mixed carotenoids
omega-3 fatty acids
orange
pine bark
pumpkin
riboflavin (vitamin B2)
rutin
saffron
sardines
shrimp
spinach
tomato
triphala
vegetable and fruit blend (proprietary)
vitamin A
vitamin B
vitamin C
vitamin E
water
mulberry
zeaxanthin
zinc
chickweed
morus
chrysanthemum
haliotis
polyphenols
trace minerals
goji berry
herbal blend (proprietary)
algae
3,3'-dihydroxy-B-carotene-4,4'-dione
Aronia melanocarpa
Alchornea
Avocado
anthocyanidins
anthocyanosides
beta-zeacarotene
Beef liver
Blakeslea trispora
berry
Bioflavonoids
Bee products
Barbary matrimony vine
Crocin
Carnosine
Cod Liver Oil
Cyanidin
Cornflower
Cantaloupe
Chinese Ligustrum berry
Cornus
Carotene (unspecified)
Crocetin
Cocklebur
Crypthecodinium
Celosia
Capsanthin
Currant
Dunaliella salina
Docosahexaenoic Acid
Dunaliella
Egg
Ergothioneine
Eicosapentaenoic Acid
Flavonoids
fibroblast growth factor
Rose
Squid
Squash
Other body systems supported by Bioflavonoids (mixture)
ArteriesBlood
Capillaries
Circulatory System
Eyes
Gums
Heart
Immune System
Liver
Skin
Veins