Evidence supporting the use of: Capsanthin
For the body system: Eyes
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Capsanthin is a naturally occurring carotenoid pigment found primarily in red peppers (Capsicum annuum). Its primary traditional use has been as a natural colorant in food. However, recent scientific interest has focused on its potential antioxidant properties, including benefits for eye health.
Capsanthin is structurally similar to other carotenoids like lutein and zeaxanthin, which are well-established for supporting eye health, particularly in protecting the retina from oxidative damage and reducing the risk of age-related macular degeneration (AMD). Several in vitro and animal studies suggest capsanthin has strong antioxidant and anti-inflammatory properties, which could be beneficial for ocular tissues. Some preliminary research has shown it may help reduce oxidative stress in retinal cells.
However, direct clinical evidence in humans specifically linking capsanthin intake to improved eye health or prevention of eye diseases is lacking. Most human studies on eye health focus on other carotenoids (lutein, zeaxanthin, beta-carotene), with capsanthin rarely singled out. As such, while there is a plausible scientific rationale and some early-stage experimental evidence, robust human clinical trials are still needed to confirm its effectiveness for eye support.
In summary, the use of capsanthin for eye health is based on scientific reasoning and some supportive laboratory data, but the evidence base is currently limited, and rated as moderate to low (2/5) due to the lack of direct clinical studies.
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