Evidence supporting the use of: Carotenoid
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Carotenoids, particularly lutein and zeaxanthin, are well-studied for their role in supporting eye health. These pigments are found in high concentrations in the macula of the human retina, where they help filter harmful high-energy blue wavelengths of light and act as antioxidants. Numerous epidemiological and interventional studies have demonstrated that higher dietary intake and plasma levels of lutein and zeaxanthin are associated with a reduced risk of age-related macular degeneration (AMD), a leading cause of vision loss in older adults. Randomized controlled trials, such as the Age-Related Eye Disease Study 2 (AREDS2), have shown that supplementation with these carotenoids can slow the progression of AMD in individuals at high risk. Other carotenoids like beta-carotene have also been researched, though their use is more controversial due to potential risks in smokers. The mechanisms involve antioxidant activity, blue light filtration, and maintenance of retinal structure and function. While not all studies show benefit for every population, the overall body of evidence supports the use of specific carotenoids (especially lutein and zeaxanthin) for eye health, particularly in the context of preventing or slowing AMD. Therefore, their use for supporting the eye body system is justified based on substantial scientific evidence.

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