Evidence supporting the use of: Cyanidin
For the body system: Eyes

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cyanidin is an anthocyanin, a type of flavonoid pigment found abundantly in many fruits and vegetables, particularly in berries such as blackberries, blueberries, and cherries. Cyanidin and its glycosides have attracted attention for their antioxidant properties, which are hypothesized to benefit eye health by protecting ocular tissues from oxidative stress, a factor in conditions such as age-related macular degeneration (AMD) and cataracts. Preclinical studies (in vitro and animal models) have shown that cyanidin can scavenge free radicals and may inhibit pathways involved in retinal damage. Some small-scale human studies indicate that anthocyanin-rich extracts can improve dark adaptation and reduce eye fatigue, but these studies often use mixed anthocyanin preparations, not isolated cyanidin, and are limited by sample size and methodological rigor.

To date, there are no large, high-quality clinical trials directly demonstrating that cyanidin, specifically, provides significant or unique support to the eyes in humans. Therefore, while the biological plausibility and some initial studies provide a scientific rationale, the direct clinical evidence is limited. The use of cyanidin for eye health is scientifically plausible but not robustly validated, justifying a rating of 2/5 for evidence.

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