Relationship: Eyes and EPA (eicosapentaenoic acid)

Evidence supporting the use of: EPA (eicosapentaenoic acid)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Eicosapentaenoic acid (EPA) is an omega-3 polyunsaturated fatty acid found primarily in marine sources such as fish oil. There is moderate scientific evidence supporting its role in eye health, particularly for its anti-inflammatory properties. EPA, often combined with docosahexaenoic acid (DHA), has been studied for its impact on dry eye syndrome and age-related macular degeneration (AMD). The Age-Related Eye Disease Study 2 (AREDS2), a large randomized controlled trial, evaluated supplementation with EPA and DHA in addition to other nutrients for AMD. While the addition of EPA and DHA did not provide statistically significant additional benefit for AMD progression compared to the original AREDS formulation, some secondary analyses and smaller studies suggest omega-3s may help reduce symptoms of dry eye disease, likely due to their ability to modulate inflammation and support tear production.

Professional organizations like the American Academy of Ophthalmology acknowledge the potential benefits of omega-3 supplementation for dry eye, but note that evidence is mixed and more research is needed. Overall, the use of EPA for eye health is scientifically plausible, especially in the context of anti-inflammatory effects, but the clinical evidence is moderate and not definitive for all eye conditions. EPA is not a cure-all, but may be useful as part of a broader strategy for supporting ocular surface health.

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Other body systems supported by EPA (eicosapentaenoic acid)

Arteries
Blood
Brain
Circulatory System
Eyes
Heart
Immune System
Intestinal System
Joints
Liver
Lungs
Prostaglandins
Reproductive System
Respiratory System
Skin

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Evidence supporting the use of: EPA (eicosapentaenoic acid)
For the body system: Eyes

Table of Contents

Synopsis

Other ingredients that support Eyes

Other body systems supported by EPA (eicosapentaenoic acid)

Products containing EPA (eicosapentaenoic acid)

Health Concerns

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Evidence supporting the use of: EPA (eicosapentaenoic acid)For the body system: Eyes

Table of Contents

Synopsis

Other ingredients that support Eyes

Other body systems supported by EPA (eicosapentaenoic acid)

Products containing EPA (eicosapentaenoic acid)

Evidence supporting the use of: EPA (eicosapentaenoic acid)
For the body system: Eyes