Evidence supporting the use of: Fish oil
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Fish oil, rich in omega-3 fatty acids (primarily EPA and DHA), has a scientifically validated role in supporting eye health, particularly in relation to dry eye syndrome and age-related macular degeneration (AMD). Several randomized, controlled trials and epidemiological studies have shown that supplementation with omega-3s can reduce symptoms of dry eye disease by improving tear production and reducing inflammation. For AMD, the evidence is more nuanced: large studies such as the Age-Related Eye Disease Study 2 (AREDS2) found that adding omega-3s to an antioxidant supplement regimen did not significantly reduce the progression to advanced AMD. However, some observational studies suggest that higher dietary intake of omega-3s is associated with a lower risk of developing AMD. The mechanism is thought to involve anti-inflammatory effects and maintenance of retinal cell integrity, as DHA is a major structural component of the retina. Despite some conflicting results, there is enough scientific evidence to support the use of fish oil for certain aspects of eye health, especially for alleviating dry eye symptoms, earning it a moderate evidence score.

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3,3'-dihydroxy-B-carotene-4,4'-dione
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algal oil
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anchovies
anthocyanidins
anthocyanins
anthocyanosides
apricot
Aronia melanocarpa
astaxanthin
avocado
barbary matrimony vine
bee products
Beef liver
berry
beta-carotene
beta-zeacarotene
bilberry
bioflavonoids
black currant
blackberry
Blakeslea trispora
blueberry
broccoli
calamari oil
cantaloupe
capsanthin
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carotene (unspecified)
carrot
Celosia
chickweed
Chinese Ligustrum berry
chrysanthemum
citicoline
cocklebur
cod liver oil
cornflower
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crocetin
crocin
Crypthecodinium
cryptoxanthin
currant
cyanidin
d-alpha tocopherol
DHA (docosahexaenoic acid)
docosahexaenoic Acid
Dunaliella
Dunaliella salina
egg
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
ergothioneine
Eyebright
Fagopyrum
fat liver oil
fatty acids
fibroblast growth factor
fish
fish oil
flavoglycosides
flavonoids
flavonols
fruit
fruit and vegetable blend (proprietary)
Gac
gamma-carotene
ginkgo flavone glycoside
Glutathione
goji berry
gooseberry
Haematococcus pluvialis
haliotis
herbal blend (proprietary)
huckleberry
hyaluronic acid
Idebenone
kale
L-carnosine
L-taurine
Ligustrum
lipids
lutein
Lycium
marigold
Marine fat
Marine lipid
Melatonin
Mineral ascorbate
mixed carotenoids
Morus
Mulberry
N-Acetyl Carnosine
Oligomeric proanthocyanidins
omega-3 fatty acids
orange
Phaffia rhodozyma
pine bark
Polygonum
polyphenols
polyunsaturated fat
proanthocyanidins
procyanidol
pumpkin
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riboflavin (vitamin B2)
rose
rue
rutin
saffron
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Schizochytrium
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spinach
Tagetes
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trace minerals
Triphala
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vegetable and fruit blend (proprietary)
vitamin A
vitamin B
vitamin C
vitamin E
Xanthophyll
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