Flavonoids are a diverse group of polyphenolic compounds found in fruits, vegetables, tea, and other plant-based foods. Scientific evidence supports the potential benefits of flavonoids for eye health, particularly in relation to their antioxidant, anti-inflammatory, and vascular protective effects. Several studies have investigated the association between dietary flavonoid intake and reduced risk of eye diseases, such as age-related macular degeneration (AMD) and cataracts. Flavonoids, including subclasses like anthocyanins, flavonols, and flavan-3-ols, are known to help protect ocular tissues from oxidative stress, which is a key factor in the pathogenesis of many eye disorders.

Specific flavonoids, such as quercetin, rutin, and the anthocyanins in bilberry and blueberries, have been studied for their ability to improve retinal blood flow, reduce inflammation, and stabilize blood vessels in the eyes. Some clinical and observational studies have suggested that higher dietary intake of flavonoids correlates with better visual function and a lower incidence of AMD and cataracts, although the data are not uniformly conclusive and more high-quality randomized controlled trials are needed. Overall, while the evidence is not overwhelmingly strong, it is sufficient to support a scientific rationale for the use of flavonoids as supportive agents for ocular health.

References:

• Manach, C. et al. (2004). Polyphenols: food sources and bioavailability. The American Journal of Clinical Nutrition, 79(5), 727-747.
• Ma, L. et al. (2016). The role of dietary anthocyanins and flavonoids in the prevention of vision loss. Nutrition Reviews, 74(9), 624-634.