Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Flavonols, a subclass of flavonoids found in many fruits and vegetables (notably in onions, kale, apples, and berries), have been investigated for their potential benefits to eye health, primarily due to their antioxidant properties. Scientific studies suggest that oxidative stress plays a significant role in the development and progression of common eye disorders, such as age-related macular degeneration (AMD) and cataracts. Flavonols, particularly quercetin, have demonstrated the ability to scavenge free radicals and reduce oxidative damage in ocular tissues in laboratory and some animal studies.

However, while preclinical research is promising, clinical evidence in humans is limited. Observational studies have suggested that diets rich in flavonoids, including flavonols, are associated with a reduced risk of cataracts and AMD, but these studies cannot establish causation and often involve a variety of dietary factors. Few interventional trials specifically testing flavonol supplementation for eye health exist, and those that do are generally small and preliminary.

In summary, the rationale for using flavonols to support the eyes is based primarily on mechanistic and epidemiological evidence rather than robust clinical trials. Therefore, while there is some scientific foundation, the direct evidence supporting flavonols for eye health in humans is currently modest.

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Douglas Laboratories Ultra Preventive 50+ -EZ Swallow