Evidence supporting the use of: Marine fat
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Marine fat, particularly sources rich in omega-3 polyunsaturated fatty acids such as EPA and DHA (commonly found in fish oil), has substantial scientific support for its use in supporting the eye body system. Numerous clinical and epidemiological studies have demonstrated that omega-3 fatty acids play a critical role in maintaining retinal structure and function. The retina contains high concentrations of DHA, and adequate intake has been linked to a reduced risk of age-related macular degeneration (AMD) and dry eye syndrome. Randomized controlled trials, such as those referenced by the Age-Related Eye Disease Study 2 (AREDS2), found that supplementation with omega-3 fatty acids may help slow the progression of AMD in certain populations, though results are mixed regarding the magnitude of benefit. Additionally, omega-3s are thought to exert anti-inflammatory effects that can benefit overall ocular surface health, particularly in individuals with dry eye disease. While not a cure, marine fat-derived omega-3 supplementation is widely recommended by ophthalmologists and is supported by guidelines from professional associations for maintaining eye health, especially in populations at risk for degenerative eye conditions. However, some recent meta-analyses have called for more high-quality trials to confirm these benefits, particularly for AMD, so the evidence, while strong, is not unequivocal.

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