Evidence supporting the use of: Marine oil (unspecified)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Marine oil, often referring to fish oil or oils derived from marine sources rich in omega-3 fatty acids (notably EPA and DHA), is supported by a substantial body of scientific evidence for its benefit to the eyes, particularly in maintaining ocular health and potentially reducing the risk of certain eye conditions. The primary mechanism is thought to be the anti-inflammatory properties of omega-3 fatty acids, which are integral to the structural and functional integrity of retinal cells and may help in the prevention or management of dry eye syndrome and age-related macular degeneration (AMD).

Multiple randomized controlled trials and meta-analyses have shown that supplementation with marine oil can lead to improvements in symptoms of dry eye disease, likely due to reductions in ocular surface inflammation and improved tear film stability. For example, the DREAM study (Dry Eye Assessment and Management) and other clinical trials have explored the efficacy of omega-3 supplementation in dry eye, with mixed but generally positive results.

Furthermore, observational studies suggest that higher dietary intake of marine-derived omega-3s is associated with a lower risk of advanced AMD. The Age-Related Eye Disease Study 2 (AREDS2) did not show a significant benefit for omega-3s in slowing AMD progression, but other population studies and mechanistic research continue to support their protective role.

Overall, while some results are mixed and ongoing research is warranted, the use of marine oil for eye health is grounded in scientific evidence, especially for dry eye and possibly for AMD prevention.

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