Evidence supporting the use of: Nerve growth factor
For the body system: Eyes

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Nerve Growth Factor (NGF) is a neurotrophin essential for the growth, maintenance, and survival of neurons. Its use in supporting the ocular system, particularly in treating certain eye disorders, is scientifically validated. Multiple studies have demonstrated the efficacy of NGF in promoting corneal healing and nerve regeneration. For example, recombinant human NGF (rhNGF) eye drops, branded as cenegermin (Oxervate), have received regulatory approval in both the European Union and the United States for the treatment of neurotrophic keratitis, a rare degenerative corneal disease. Clinical trials have shown that topical NGF can improve corneal healing rates and restore sensitivity in affected patients. The mechanism underlying NGF’s effectiveness in the eye involves its ability to stimulate the regeneration of corneal nerves and epithelial cells, leading to improved ocular surface health and function. Beyond neurotrophic keratitis, research is ongoing regarding NGF’s potential in treating other ocular conditions such as glaucoma, retinitis pigmentosa, and optic neuropathies, though these uses remain experimental. In summary, the use of NGF for supporting the eye, particularly in the context of corneal nerve damage and healing, is grounded in robust scientific evidence, with regulatory approvals underscoring its clinical utility for specific ophthalmic indications.

More about Nerve growth factor
More about Eyes

Other body systems supported by Nerve growth factor

Brain
Eyes
Nerves

Products containing Nerve growth factor

We currently have no products on Vitabase that contain this ingredient.